A functional chromaffinoma, usually benign, derived from adrenal medullary tissue cells and characterized by the secretion of catecholamines, resulting in hypertension, which may be paroxysmal and associated with attacks of palpitation, headache, nausea, dyspnea, anxiety, pallor, and profuse sweating. P. is often hereditary, not only in phacomas such as Hippel-Lindau disease, neurofibromatosis, and familial endocrine neoplasia, but also as an isolated defect [MIM*171300] as an autosomal dominant trait. SEE ALSO: paraganglioma.

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pheo·chro·mo·cy·to·ma or Brit phaeo·chro·mo·cy·to·ma .fē-ə-'krō-mə-sə-'tō-mə, -sī- n, pl -mas also -ma·ta -mət-ə a tumor that is derived from chromaffin cells and is usu. associated with paroxysmal or sustained hypertension

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pheo·chro·mo·cy·to·ma (fe″o-kro″mo-si-toґmə) [pheochromocyte + -oma] a usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. Because of increased secretion of epinephrine and norepinephrine, hypertension is a cardinal symptom; it may be persistent or intermittent. During severe attacks, there may be headache; sweating; palpitation and tremor; pallor or flushing of the face; nausea and vomiting; pain in the chest and abdomen; and paresthesias of the extremities. Called also medullary chromaffinoma, medullary paraganglioma, chromaffin cell tumor, and pheochromoblastoma.

Medical dictionary. 2011.

Look at other dictionaries:

  • Pheochromocytoma — Infobox Disease Name = Pheochromocytoma Caption = Medulla visible at bottom right. DiseasesDB = 9912 ICD10 = ICD10|C|74|1|c|73 ICD9 = ICD9|255.6 ICDO = ICDO|8700|0 OMIM = 171300 MedlinePlus = 000340 eMedicineSubj = med eMedicineTopic = 1816… …   Wikipedia

  • pheochromocytoma — /fee oh kroh moh suy toh meuh/, n., pl. pheochromocytomas, pheochromocytomata / meuh teuh/. Pathol. a tumor of the sympathetic nervous system or adrenal medulla, that produces excess norepinephrine and epinephrine and causes hypertension,… …   Universalium

  • pheochromocytoma — noun (plural mas; also pheochromocytomata) Etymology: New Latin, from International Scientific Vocabulary pheochromocyte chromaffin cell (from pheochrome chromaffin from Greek phaios dusky, gray + International Scientific Vocabulary chrome +… …   New Collegiate Dictionary

  • pheochromocytoma — noun A neuroendocrine tumour of the medulla of the adrenal glands …   Wiktionary

  • pheochromocytoma — pheo·chro·mo·cy·to·ma …   English syllables

  • pheochromocytoma — Tumor that forms in the center of the adrenal gland (gland located above the kidney) that causes it to make too much adrenaline. Pheochromocytomas are usually benign (noncancerous) but can cause high blood pressure, pounding headaches, heart… …   English dictionary of cancer terms

  • pheochromocytoma — noun a vascular tumor of the adrenal gland; hypersecretion of epinephrine results in intermittent or sustained hypertension • Syn: ↑phaeochromocytoma • Hypernyms: ↑tumor, ↑tumour, ↑neoplasm …   Useful english dictionary

  • medullary chromaffinoma — pheochromocytoma …   Medical dictionary

  • medullary paraganglioma — pheochromocytoma …   Medical dictionary

  • chromaffin cell tumor — pheochromocytoma …   Medical dictionary

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