penicillamine

A degradation product of penicillin; a chelating agent used in the treatment of lead poisoning, hepatolenticular degeneration, and cystinuria, and in the removal of excess copper in Wilson disease; also available as p. hydrochloride. SYN: β,β-dimethylcysteine.

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pen·i·cil·la·mine .pen-ə-'sil-ə-.mēn n an amino acid C5H11NO2S that is obtained from penicillins and is used esp. to treat cystinuria, rheumatoid arthritis, and metal poisoning (as by copper or lead)

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n.
a drug that binds metals and therefore aids their excretion (see chelating agent). It is used to treat Wilson's disease, poisoning by metals such as lead, copper, and mercury, and severe rheumatoid arthritis. It is administered by mouth and commonly causes digestive upsets and allergic reactions. Trade names: Distamine, Pendramine.

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pen·i·cil·la·mine (pen″ĭ-silґə-mēn) [USP] a degradation product of penicillin that chelates certain heavy metals; used orally to reduce the blood copper level in treatment of Wilson disease and to promote excretion of cystine in patients with cystinuria or recurrent cystine calculus formation, by forming a more soluble penicillamine-cystine disulfide. It is also used as a disease-modifying antirheumatic drug in treatment of refractory rheumatoid arthritis.

Medical dictionary. 2011.

Look at other dictionaries:

  • Penicillamine — Systematic (IUPAC) name (2 …   Wikipedia

  • Penicillamine — Pen i*cil lam*ine, n. (Chem., Med.) a substance ({C5H11NO2S}) which is a degradation product of the penicillins. Chemically it is 3 mercapto D valine. It has chelating properties and is used in medicine as an antirheumatic and to chelate copper… …   The Collaborative International Dictionary of English

  • pénicillamine — ● pénicillamine nom féminin Médicament antirhumatismal et chélateur (efficace contre les intoxications) …   Encyclopédie Universelle

  • penicillamine — [pen΄i sil′ə mēn΄, pen΄i sil′əmin] n. a white, crystalline chelating drug, C5H11NO2S, used to treat Wilson s disease, severe cases of rheumatoid arthritis, etc …   English World dictionary

  • penicillamine — penicilaminas statusas T sritis chemija formulė (CH₃)₂C(SH)CH(NH₂)COOH atitikmenys: angl. penicillamine rus. пеницилламин ryšiai: sinonimas – 2 amino 3 merkapto 3 metilbutano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • penicillamine — noun Etymology: penicillin + amine Date: 1943 an amino acid C5H11NO2S that is obtained from penicillins and is used especially in the treatment of cystinuria, rheumatoid arthritis, and poisoning by metals (as copper or lead) …   New Collegiate Dictionary

  • penicillamine — (= dimethyl cysteine) Product of acid hydrolysis of penicillin that chelates heavy metals (lead, copper, mercury) and assists in their excretion in cases of poisoning. Also used in treatment of rheumatoid arthritis although its mode of action as… …   Dictionary of molecular biology

  • penicillamine — /pen euh sil euh meen , min/, n. Pharm. a chelating agent, C5H11NO2S, produced by the degradation of penicillin, used in the treatment of severe rheumatoid arthritis and in heavy metal poisoning. [1940 45; PENICILL(IN) + AMINE] * * * …   Universalium

  • penicillamine — noun a breakdown product of penicillin used as a chelating drug to treat poisoning by heavy metals etc …   Wiktionary

  • penicillamine — pen·i·cil·la·mine …   English syllables

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