paraprotein

1. A monoclonal immunoglobulin of blood plasma, observed electrophoretically as an intense band in γ, β, or α regions, due to an isolated increase in a single immunoglobulin type as a result of a clone of plasma cells arising from the abnormal rapid multiplication of a single cell. The finding of a p. in a patient's serum indicates the presence of a proliferating clone of immunoglobulin-producing cells and may be seen in a variety of malignant, benign, or nonneoplastic diseases. 2. SYN: monoclonal immunoglobulin. [para + protein, fr. G. protos, first]

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para·pro·tein -'prō-.tēn, -'prōt-ē-ən n any of various abnormal serum globulins with unique physical and electrophoretic characteristics

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n.
an abnormal protein of the immunoglobulin series. Paraproteins appear in malignant disease of the spleen, bone marrow, liver, etc. Examples of paraproteins are myeloma globulins, Bence-Jones protein, and macroglobulin.

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para·pro·tein (par″ə-proґtēn) M component.

Medical dictionary. 2011.

Look at other dictionaries:

  • Paraprotein — Serum protein electrophoresis showing a paraprotein (peak in the gamma zone) in a patient with multiple myeloma. A paraprotein is an immunoglobulin or immunoglobulin light chain that is produced in excess by the clonal proliferation of plasma… …   Wikipedia

  • Paraprotein — M Gradient in der Elektrophorese bei Multiplen Myelom Bei den Paraproteinen handelt es sich um Eiweißkörper – meist funktionslose Immunglobuline (Antikörper) oder deren einzelne Bestandteile – im Blut oder Urin, die bei der Elektrophorese… …   Deutsch Wikipedia

  • paraprotein — ˌ noun Etymology: para (I) + protein : any of various abnormal serum globulins with unique physical and electrophoretic characteristics * * * paraprotein(æmia see para 1 2 a …   Useful english dictionary

  • paraprotein — noun A protein found in the blood only as a result of disease …   Wiktionary

  • Paraprotein — Pa|ra|pro|te|in [↑ para (5)]: bei bestimmten pathologischen Prozessen (Paraproteinämien) nachweisbare monoklonale Immunglobuline, z. B. Bence Jones u. Amyloid Proteine. * * * Pa|ra|pro|te|in, das; s, e <meist Pl.> [zu ↑para , Para u.… …   Universal-Lexikon

  • Paraprotein — Para|prote|i̱n [↑para... u. ↑Protein] s; s, e (meist Mehrz.): entartete Eiweißkörper im Blut (unwirksame Antikörperglobuline), die sich bei bestimmten Blutkrankheiten bilden …   Das Wörterbuch medizinischer Fachausdrücke

  • Paraprotein — Pa|ra|pro|te|in das; s, e (meist Plur.) <zu ↑para... u. ↑Protein> entarteter Eiweißkörper im Blut, der sich bei bestimmten Blutkrankheiten bildet (Med.) …   Das große Fremdwörterbuch

  • paraprotein — para·protein …   English syllables

  • paraprotein — n. an abnormal protein of the immunoglobulin series. Paraproteins appear in malignant disease of the spleen, bone marrow, liver, etc. Examples of paraproteins are myeloma globulins, Bence Jones protein, and macroglobulin …   The new mediacal dictionary

  • Bence-Jones-Paraprotein — Kristall des Bence Jones Proteins Bence Jones Proteine sind Proteine, welche bei der gleichnamigen Bence Jones Proteinurie im Urin auftauchen. Es handelt sich dabei um niedermolekulare, nephrotoxische (für die Nieren giftige) Paraproteine im Urin …   Deutsch Wikipedia

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