- IGG). See also demyelination, Landry’s paralysis.
* * *Guil·lain-Bar·ré syndrome .gē-.lan-.bä-'rā-, .gē-yan- n a polyneuritis of unknown cause characterized esp. by muscle weakness and paralysis called also Landry's paralysisGuillain gē-yan Georges Charles (1876-1961), andBarré bä-rā Jean Alexander (1880-1967)French neurologists. Guillain published several significant neurological studies concerning the brain and the spinal column. An authority on the spinal column in particular, he made studies of the cerebrospinal fluid and the marrow of the spinal cord. Guillain and Barré published their description of the Guillain-Barré syndrome in 1916.
* * *a disease of the peripheral nerves in which there is numbness and weakness in the limbs. It usually develops 10-20 days after a respiratory or gastrointestinal infection (commonly with Campylobacter) that provokes an allergic response in the peripheral nerves. Involvement of the respiratory muscles may require mechanical ventilation. Recovery is usually excellent although often prolonged. Treatment with immunoglobulins (intravenous) or with plasma exchange may speed recovery and reduce long-term disability. See polyradiculitis.G. Guillain (1876-1961) and A. Barré (1880-1967), French neurologists
Medical dictionary. 2011.
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