osteogenesis

The formation of bone. SYN: osteogeny, osteosis (2), ostosis (2). [osteo- + G. genesis, production]
- distraction o. a technique of inducing new bone formation by dividing a bone and applying tension through an external fixation device to lengthen the bone.
- o. imperfecta (OI) a group of connective tissue disorders of type I collagen, characterized by bone fragility, fractures on trivial trauma, skeletal deformity, blue sclerae, ligament laxity, and hearing loss. The Sillence system, which is a clinical, radiographic, and genetic classification, shows four types; inherited as autosomal dominant, caused by mutation in either the collagen type I alpha-1 gene (COL1A1) on chromosome 17q or the alpha-2 gene (COL1A2) on 7q. SYN: brittle bones.
- o. imperfecta congenita a severe form [MIM 166230], with fractures occurring before or at birth.
- o. imperfecta tarda a less severe form, with fractures occurring later in childhood.
- Type I o. imperfecta [MIM*166200] a mild form characterized by blue sclerae, hearing loss, easy bruising, prepubertal bone fragility, and short stature.
- Type II o. imperfecta [MIM*166210] a perinatal lethal form associated with stillbirth or lifespan less than 1 year; very fragile connective tissue, and radiographic findings of in utero fractures, large soft cranium, micromelia, tubular long bones, and beaded ribs.
- Type III o. imperfecta [MIM*259420] a progressive deforming form with severe bone fragility, easy fractures, triangular facies with relative macrocephaly, skeletal deformities with scoliosis, pectus and bowing of limbs, dwarfism, and radiographic findings of metaphyseal flaring of long bones with sutural bone formation. Most cases are autosomal dominant disorders, but autosomal recessive inheritance has also been described.
- Type IV o. imperfecta [MIM*166220] a moderately severe form, characterized by short stature, bone fragility, preambulatory fractures, and bowing of long bones.

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os·teo·gen·e·sis .äs-tē-ə-'jen-ə-səs n, pl -e·ses -.sēz development and formation of bone

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n.

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os·teo·gen·e·sis (os″te-o-jenґə-sis) [osteo- + -genesis] formation of bone; the development of the bones. osteogenetic adj

Medical dictionary. 2011.

Look at other dictionaries:

  • Osteogenesis — is the process of laying down new bone material by osteoblasts. It occurs in two different ways: Either by Intramembranous Osteogenesis (see intramembranous ossification), which is the direct laying down of bone into the primitive connective… …   Wikipedia

  • osteogénesis — f. histol. Formación y desarrollo del tejido óseo. Medical Dictionary. 2011. osteogénesis generación o …   Diccionario médico

  • osteogénesis — (plural osteogénesis) sustantivo femenino 1. (no contable) Área: biología Desarrollo de los huesos o del tejido óseo …   Diccionario Salamanca de la Lengua Española

  • Osteogenesis — Os te*o*gen e*sis, Osteogeny Os te*og e*ny, n. [Osteo + genesis, or the root of Gr. gi gnesqai to be born: cf. F. ost[ e]og[ e]nie.] (Physiol.) The formation or growth of bone. [1913 Webster] …   The Collaborative International Dictionary of English

  • osteogénesis — {{#}}{{LM O28433}}{{〓}} {{[}}osteogénesis{{]}} ‹os·te·o·gé·ne·sis› {{◆}}(pl. osteogénesis){{◇}} {{《}}▍ s.f.{{》}} Formación de los huesos. {{★}}{{\}}ETIMOLOGÍA:{{/}} Del griego ostéon (hueso) y génesis …   Diccionario de uso del español actual con sinónimos y antónimos

  • osteogénesis — ► sustantivo femenino BIOLOGÍA Proceso de formación de los huesos y del tejido óseo. IRREG. plural osteogénesis …   Enciclopedia Universal

  • Osteogenesis — kaulo formavimasis statusas T sritis histologija, ląstelių chemija, histologinė chemija, audinių kultūra atitikmenys: lot. Osteogenesis ryšiai: platesnis terminas – kaulinis audinys siauresnis terminas – kauliškasis audinys siauresnis terminas –… …   Veterinarinės anatomijos, histologijos ir embriologijos terminai

  • Osteogenesis — kaulų susidarymas statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Osteogenesis ryšiai: platesnis terminas – pirminių griaučių raida siauresnis terminas – kremzlinė osteogenezė siauresnis terminas – membraninė… …   Veterinarinės anatomijos, histologijos ir embriologijos terminai

  • osteogenesis — noun Etymology: New Latin Date: 1830 development and formation of bone …   New Collegiate Dictionary

  • osteogenesis — Production of bone …   Dictionary of molecular biology

  • osteogenesis — osteogenetic /os tee oh jeuh net ik/, osteogenous /os tee oj euh neuhs/, adj. /os tee euh jen euh sis/, n. the formation of bone. [1820 30; OSTEO + GENESIS] * * * …   Universalium

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