- A protein found in osteoblasts and dentin; contains γ-carboxyglutamyl residues; has a role in mineralization and calcium ion homeostasis. SYN: bone Gla protein.
* * *os·teo·cal·cin -'kal-sən n a protein that is found in the extracellular matrix of bone and in the serum of circulating blood, is produced by osteoblasts esp. in the presence of vitamin K but is not a collagen, and when present at excessive levels in serum may be indicative of various disorders (as Paget's disease or postmenopausal osteoporosis) of bone metabolism
* * *os·teo·cal·cin (os″te-o-kalґsin) a vitamin Kâ€“dependent, calcium-binding bone protein, the most abundant noncollagen protein in bone; increased serum concentrations are a marker of increased bone turnover in disease states. Called also bone Gla protein.
Medical dictionary. 2011.
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Osteocalcin — Masse/Länge Primärstruktur 49 Aminosäuren … Deutsch Wikipedia
Osteocalcin — Bone gamma carboxyglutamate (gla) protein PDB rendering based on 1q8h … Wikipedia
osteocalcin — (= bone g carboxyglutamic acid protein: BGP) Polypeptide of 50 residues formed from a 76 77 amino acid precursor, and found in the extracellular matrix of bone. Binds hydroxyapatite. Has limited homology of its leader sequence with that of other… … Dictionary of molecular biology
osteocalcin — noun A protein found in bone and dentin, manufactured by osteoblasts. It plays a role in mineralization and calcium ion homeostasis … Wiktionary
bone Gla protein — osteocalcin … Medical dictionary
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