myeloblast

An immature cell (10 to 18 μm in diameter) in the granulocytic series, occurring normally in bone marrow, but not in the circulating blood (except in certain diseases). When stained with the usual dyes, the cytoplasm is light blue, nongranular, and variable in amount, sometimes being only a thin rim around the nucleus; the latter is deep purple-blue with finely divided, punctate, threadlike chromatin that is somewhat condensed at the periphery. A few light blue nucleoli are usually present in the nucleus, and these generally disappear as the m. matures into a promyelocyte and then a myelocyte. Myeloblasts ordinarily yield a negative reaction with peroxidase. [myelo- + G. blastos, germ]

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my·e·lo·blast 'mī-ə-lə-.blast n a large mononuclear nongranular bone marrow cell esp one that is a precursor of a myelocyte compare LEUKOBLAST
my·e·lo·blas·tic .mī-ə-lə-'blas-tik adj

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n.
the earliest identifiable cell that gives rise to a granulocyte, having a large nucleus and scanty cytoplasm. It is normally found in the blood-forming tissue of the bone marrow, but may appear in the blood in a variety of diseases, most notably in acute myeloblastic leukaemia. See also granulopoiesis.
myeloblastic adj.

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my·elo·blast (miґə-lo-blast) [myelo- + -blast] an immature cell found in the bone marrow and not normally in the peripheral blood, the most primitive precursor in the granulocytic series, which develops into the promyelocyte. Myeloblasts have fine, evenly distributed chromatin, several nucleoli, and a nongranular basophilic cytoplasm.

Medical dictionary. 2011.

Look at other dictionaries:

  • Myeloblast — Code TH H2.00.04.3.04002 The myeloblast is a unipotent stem cell, which will differentiate into one of the actors of the Granulocyte series …   Wikipedia

  • myeloblast — [mī′ə lō blast΄] n. [ MYELO + BLAST] a bone marrow cell, not normally in the blood, that develops into certain white blood cells (neutrophils, eosinophils, and basophils) …   English World dictionary

  • myeloblast — myeloblastic, adj. /muy euh leuh blast /, n. Cell Biol. an immature myelocyte. [1900 05; MYELO + BLAST] * * * ▪ physiology       immature blood cell, found in bone marrow, that gives rise to white blood cells of the granulocytic series… …   Universalium

  • myeloblast — noun Etymology: International Scientific Vocabulary Date: circa 1904 a large mononuclear nongranular bone marrow cell; especially one that is a precursor of a myelocyte • myeloblastic adjective …   New Collegiate Dictionary

  • Myeloblast — Myeloblasten sind Vorläuferzellen einer bestimmten Population weißer Blutkörperchen (Leukozyten). Sie sind die ersten morphologisch identifizierbaren Zellen der Myelopoese (Granulopoese) im Knochenmarkausstrich. Sie sind die einzigen Zellen… …   Deutsch Wikipedia

  • myeloblast — noun An immature cell of bone marrow that develops into a myelocyte …   Wiktionary

  • Myeloblast — Mye|lo|blạst [↑myelo... u. ↑...blast] m; en, en (meist Mehrz.): Keimzellen des Knochenmarks, Vorstufe der ↑Myelozyten …   Das Wörterbuch medizinischer Fachausdrücke

  • Myeloblast — My|e|lo|blast* der; en, en (meist Plur.) <zu gr. blastós »Spross, Trieb«> Keimzelle des Knochenmarks (Med.) …   Das große Fremdwörterbuch

  • myeloblast — n. bone marrow cells which have not yet fully developed (Anatomy) …   English contemporary dictionary

  • myeloblast — my·e·lo·blast …   English syllables

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