Fragile X chromosome

An X chromosome with a heritable fragile site associated with a frequent form of mental retardation — the fragile X syndrome. The fragile X chromosome was first sighted by Dr. Herbert A. Lubs in 1969 who termed it the "marker X.". The fragile X is also called FRAXA. It was the first fragile site found on the X chromosome. The fragile X chromosome is due to a trinucleotide repeat sequence (a recurring motif of 3 bases) in the DNA at that spot.

Medical dictionary. 2011.

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  • Chromosome — A visible carrier of the genetic information. The 3 billion bp (base pairs) in the human genome are organized into 24 distinct, physically separate microscopic units called chromosomes. All genes are arranged linearly along the chromosomes. The… …   Medical dictionary

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