l-Phenylalanine mustard; l-sarcolysine; l-3-[p-[bis(2-chloroethyl)amino]phenyl]alanine; a phenylalanine derivative of nitrogen mustard; an alkalylating antineoplastic agent.

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mel·pha·lan 'mel-fə-.lan n an antineoplastic drug C13H18Cl2N2O2 that is a derivative of nitrogen mustard and is used esp. in the treatment of multiple myeloma called also L-PAM, phenylalanine mustard, sarcolysin

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a drug used to treat various types of cancer, particularly myeloma but also including tumours of the breast and ovaries and Hodgkin's disease. It is administered by mouth or injection. Side-effects include digestive upsets, mouth ulcers, and temporary hair loss. Trade name: Alkeran.

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mel·pha·lan (melґfə-lan) [USP] a cytotoxic alkylating agent that is the L-phenylalanine derivative of mechlorethamine, used as an antineoplastic, primarily for treatment of multiple myeloma, administered orally or intravenously; it is also used in regional limb perfusion for melanoma of the extremity, administered by arterial infusion. Called also L-sarcolysin and L-phenylalanine mustard (L-PAM).

Medical dictionary. 2011.

Look at other dictionaries:

  • Melphalan — Systematic (IUPAC) name 4 [bis(chloroethyl)amino]phenylalanine Clinical data Trade names Alkeran …   Wikipedia

  • melphalan — melphalan. См. мелфалан. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • melphalan — noun Etymology: probably from methanol + phenylalanine Date: 1960 an antineoplastic drug C13H18Cl2N2O2 …   New Collegiate Dictionary

  • melphalan — noun A particular drug used in chemotherapy …   Wiktionary

  • melphalan — mel·pha·lan …   English syllables

  • melphalan — n. a drug (an alkylating agent) used to treat various types of cancer, particularly myeloma but also including tumours of the breast and ovaries and Hodgkin s disease. It is administered by mouth or injection. Side effects include digestive… …   The new mediacal dictionary

  • melphalan — A drug that is used to treat multiple myeloma and ovarian epithelial cancer and is being studied in the treatment of other types of cancer. It belongs to the family of drugs called alkylating agents. Also called Alkeran …   English dictionary of cancer terms

  • melphalan — noun antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies • Syn: ↑Alkeran • Usage Domain: ↑trade name (for: ↑Alkeran) • Hypernyms: ↑antineoplastic, ↑ …   Useful english dictionary

  • Мелфалан (Melphalan) — лекарственное вещество; применяется для лечения различных видов злокачественных опухолей, в том числе злокачественной меланомы, опухолей молочной железы и яичников, а также болезни Ходжкина. Назначается внутрь или в инъекциях. Возможные побочные… …   Медицинские термины

  • L-phenylalanine mustard — melphalan …   Medical dictionary

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