- A class of oral glucose-lowering drugs that act by closing ATP-dependent potassium channels in pancreatic beta cells, thus causing calcium channel opening and subsequent insulin release.
* * *pl. n.
Medical dictionary. 2011.
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meglitinides — pl. n. a group of oral hypoglycaemic drugs, including repaglinide (NovoNorm) and nateglinide (Starlix), used for treating type 2 diabetes mellitus. They act by stimulating insulin release from the pancreas and should be taken before each meal … The new mediacal dictionary
Meglitinide — Meglitinides, aka Glinides , are a class of drugs used treat diabetes type 2. They bind to an ATP dependent K+ (KATP) channel on the cell membrane of pancreatic beta cells in a similar manner to sulfonylureas but at a separate binding site.… … Wikipedia
Anti-diabetic medication — Anti diabetic medications treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral… … Wikipedia
Repaglinide — Systematic (IUPAC) name (S) (+) 2 ethoxy 4 [2 (3 methyl 1 [2 (piperidin 1 yl)phenyl]butylamino) 2 oxoethyl]benzoic acid Clinical data Trade names … Wikipedia
Biguanide — IUPAC na … Wikipedia
Nateglinide — Systematic (IUPAC) name 3 phenyl 2 [(4 propan 2 ylcyclohexanecarbonyl)amino]propanoic acid Clinical data Trade names St … Wikipedia
Mitiglinide — Systematic (IUPAC) name (2S) 2 benzyl 4 [(3aR,7aS) octahydro 2H isoindol 2 yl] 4 oxobutanoic acid Clinical data AHFS/ … Wikipedia
Glipizide — Not to be confused with gliclazide or glyburide. Glipizide Systematic (IUPAC) name N (4 [N (cyclohexylcarbamoyl)sulfamoyl]phenethyl) 5 methylpyrazine 2 carboxamide … Wikipedia
Glimepiride — Systematic (IUPAC) name 3 ethyl 4 methyl N (4 [N ((1r,4r) 4 methylcyclohexylcarbamoyl)sulfamoyl]phenethyl) 2 oxo 2,5 dihydro 1H pyrrole 1 carboxamide Clinical … Wikipedia
Metformin — Chemical structure (top) and ball and stick model (bottom) of metformin System … Wikipedia