- Abnormal proliferation of mast cells in a variety of tissues; may be systemic, involving a variety of organs, or cutaneous (urticaria pigmentosa). [mastocyte + G. -osis, condition]- diffuse m. infiltration of many organ systems by mast cells with varied clinical manifestations that can include fever, weight loss, flushing, bronchospasm, rhinorrhea, palpitations, dyspnea, diarrhea, gastrointestinal bleeding, and hypotension. SYN: systemic m..- diffuse cutaneous m. a benign process consisting of focal cutaneous infiltrates composed of mast cells; lesions are flat or slightly elevated, form wheals and itch when stroked; bone lesions may occur.
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* * *mas·to·cy·to·sis (mas″to-si-toґsis) [masto- + cytosis] a group of rare diseases characterized by infiltrates of mast cells in the tissues and sometimes other organs. The group includes diffuse and systemic m., mastocytoma, urticaria pigmentosa, and telangiectasia macularis eruptiva perstans.
Medical dictionary. 2011.
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Mastocytosis — Classification and external resources Micrograph of mastocytosis. Skin biopsy. H E stain. ICD 10 Q … Wikipedia
mastocytosis — /mas toh suy toh sis/, n. Pathol. an overproduction of mast cells in body tissues. [MAST (CELL) + O + CYTE + OSIS] * * * … Universalium
mastocytosis — noun A disorder caused by an overabundance of mastocytes in a persons body … Wiktionary
mastocytosis — /mas toh suy toh sis/, n. Pathol. an overproduction of mast cells in body tissues. [MAST (CELL) + O + CYTE + OSIS] … Useful english dictionary
mastocytosis syndrome — an episodic syndrome occurring in certain patients with systemic mastocytosis, usually those with skin lesions, bone lesions, and hepatosplenomegaly, presumably associated with histamine release from degranulation of mast cells, and characterized … Medical dictionary
Diffuse cutaneous mastocytosis — has diffuse involvement in which the entire integument may be thickened and infiltrated with mast cells to produce a peculiar orange color, giving rise to the term homme orange. :616 See also Mastocytosis Skin lesion References ^ James,… … Wikipedia
diffuse mastocytosis — diffuse cutaneous mastocytosis a condition in which the entire skin is thickened, lichenified, and leathery in appearance and accompanied by generalized erythroderma and intense pruritus as a result of widespread infiltration with mast cells. In… … Medical dictionary
systemic mastocytosis — a condition in which there are mast cell infiltrates in noncutaneous tissues, with or without cutaneous lesions; the most common sites are the liver, spleen, bone, lymph nodes, and gastrointestinal tract. See also mastocytosis syndrome, under… … Medical dictionary
systemic mastocytosis — A rare disease in which too many mast cells (a type of immune system cell) are found in the skin, bones, joints, lymph nodes, liver, spleen, and gastrointestinal tract. Mast cells give off chemicals such as histamine that can cause flushing (a… … English dictionary of cancer terms
mast cell disease — mastocytosis … Medical dictionary