A clinical illness produced by the brown recluse spider, Loxosceles reclusus, of North America; characterized by gangrenous slough at the site of the bite, nausea, malaise, fever, hemolysis, and thrombocytopenia.

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lox·os·ce·lism läk-'säs-ə-.liz-əm n a painful condition resulting from the bite of a spider of the genus Loxosceles and esp. the brown recluse spider (L. reclusa) that is characterized by local necrosis of tissue and sometimes systemic symptoms of poisoning

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lox·os·ce·lism (lok-sosґə-liz-əm) a form of arachnidism caused by the bite of Loxosceles laeta (the brown spider) or L. reclusa (the brown recluse spider), seen from South America to southern North America; it begins with a painful erythematous vesicle and progresses to a gangrenous slough of the affected area.

Loxoscelism with necrosis in an 8-year-old boy, caused by a bite by a brown recluse spider (Loxosceles reclusa).

Medical dictionary. 2011.

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