- An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesteryl ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish eye disease. SYN: lecithin acyltransferase.
Medical dictionary. 2011.
Look at other dictionaries:
Lecithin-cholesterol acyltransferase — (LCAT, also called phosphatidylcholine sterol O acyltransferase) is an enzyme which converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol) which is then sequestered into the core of a lipoprotein particle… … Wikipedia
Lecithin cholesterol acyltransferase deficiency — Classification and external resources ICD 10 E78.6 ICD 9 272.5 … Wikipedia
Lecithin-Cholesterin-Acyltransferase — Masse/Länge Primärstruktur 416 Aminosäuren … Deutsch Wikipedia
Acyltransferase — Acyl Acyltransferase is a type of transferase enzyme that acts upon acyl groups. Examples include: Glyceronephosphate O acyltransferase Lecithin cholesterol acyltransferase See also Acetyltransferase … Wikipedia
lecithin — Traditional term for 1,2 diacyl sn glycero 3 phosphocholines or 3 sn phosphatidylcholines, phospholipids that on hydrolysis yield two fatty acid molecules and a molecule each of glycerophosphoric acid and choline. In some varieties of l., both… … Medical dictionary
Phosphatidylcholine-sterol O-acyltransferase — In enzymology, a phosphatidylcholine sterol O acyltransferase (EC number|18.104.22.168) is an enzyme that catalyzes the chemical reaction:phosphatidylcholine + a sterol ightleftharpoons 1 acylglycerophosphocholine + a sterol esterThus, the two… … Wikipedia
LCAT — • lecithin cholesterol acyltransferase … Dictionary of medical acronyms & abbreviations
LCAT — Abbreviation for lecithin cholesterol acyltransferase. * * * lecithin cholesterol acyltransferase * * * lecithin cholesterol acyltransferase; see phosphatidylcholineâ€“sterol O acyltransferase … Medical dictionary
Choline acetyltransferase — Identifiers EC number 22.214.171.124 CAS number 9012 78 6 … Wikipedia
lipid — /lip id, luy pid/, n. Biochem. any of a group of organic compounds that are greasy to the touch, insoluble in water, and soluble in alcohol and ether: lipids comprise the fats and other esters with analogous properties and constitute, with… … Universalium