isoniazid

Isonicotinic acid hydrazide; first-line and probably most commonly used antituberculosis drug. Organisms rapidly develop resistance against this drug if it is used alone in the treatment of active disease. Hepatic toxicity is the major side effect.

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iso·ni·a·zid .ī-sə-'nī-ə-zəd n a crystalline compound C6H7N3O used in treating tuberculosis called also isonicotinic acid hydrazide

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n.
a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is usually given in conjunction with other antibiotics. Occasional side-effects include digestive disturbances and dry mouth; high doses or prolonged treatment may cause inflammation of the nerves, which can be countered by including pyridoxine (vitamin B6) in the preparation.

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iso·ni·a·zid (INH) (i″so-niґə-zid) [USP] an antibacterial, used as a tuberculostatic, administered orally and intramuscularly.

Medical dictionary. 2011.

Look at other dictionaries:

  • Isoniazid — Systematic (IUPAC) name isonicotinohydrazide …   Wikipedia

  • isoniazid — ☆ isoniazid [ī′sō nī′ə zid΄, ī′sənī′ə zid΄ ] n. [ ISO + NI(COTINIC) + (HYDR)AZ(INE) + ID] an antibacterial drug, C6H7N3O, used in treating and preventing tuberculosis …   English World dictionary

  • Isoniazid — Strukturformel Allgemeines Freiname Isoniazid Andere Namen …   Deutsch Wikipedia

  • isoniazid — /uy seuh nuy euh zid/, n. Pharm. a white, crystalline, water soluble solid, C6H7N3O, used in the treatment of tuberculosis. [1950 55; short for ISONICOTINIC ACID HYDRAZIDE] * * * ▪ drug also called  isonicotinic acid hydrazide (INH)        drug… …   Universalium

  • Isoniazid — I|so|ni|a|zid [Kurzw. aus Isonicotinsäurehydrazid], das; s: als Nicotinsäure Antimetabolit wirkendes Tuberkulosemittel. * * * Isoniazid   das, s, Tuberkulostatika …   Universal-Lexikon

  • isoniazid — isonicotinic acid hydrazide; = INH; n. a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is given in conjunction with other antibiotics. Occasional side… …   The new mediacal dictionary

  • isoniazid — noun Etymology: is + nicotinic acid + hydrazide Date: 1952 a crystalline compound C6H7N3O used in treating tuberculosis …   New Collegiate Dictionary

  • isoniazid — noun A medication used in the prevention and treatment of tuberculosis, having the chemical formula CHNO …   Wiktionary

  • Isoniazid — Iso|ni|azi̱d [Kurzwort aus ↑Isonikotinsäurehydrazid] s; [e]s: = Isonikotinsäurehydrazid …   Das Wörterbuch medizinischer Fachausdrücke

  • Isoniazid — Iso|ni|azid das; s Kurzw. aus Isonikotinsäurehydrazid> wichtiges ↑Chemotherapeutikum zur Bekämpfung der Tuberkulose …   Das große Fremdwörterbuch

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