- A cytokine (chemokine) derived from endothelial cells, fibroblasts, keratinocytes, macrophages, and monocytes which causes chemotaxis of neutrophils and T-cell lymphocytes. SYN: anionic neutrophil-activating peptide, monocyte-derived neutrophil chemotactic factor, neutrophil chemotactant factor, neutrophil-activating factor.
* * *(IL-8) a chemokine produced by monocytes, endothelial cells, and other cells that acts as a chemotactic and activator for neutrophils and may play a role in the extravasation of neutrophils in inflammation.
Medical dictionary. 2011.
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