hypogonadism

Inadequate gonadal function, as manifested by deficiencies in gametogenesis and/or the secretion of gonadal hormones; results in atrophy or deficient development of secondary sexual characteristics and, when occurring in prepubertal males, in altered body habitus characterized by a short trunk and long limbs.
- familial hypogonadotropic h. [MIM*312100 & MIM*307300] a group of disorders characterized by failure of sexual development, owing to inadequate secretion of pituitary gonadotropins; perhaps X-linked, but probably autosomal dominant and recessive modes of inheritance also exist.
- hypergonadotropic h. defective gonadal development or function of the gonads, resulting from elevated levels of gonadotropins.
- hypogonadotropic h. defective gonadal development or function, or both, resulting from inadequate secretion of pituitary gonadotropins. SYN: hypogonadotropic eunuchoidism, secondary h..
- male h. SYN: eunuchoidism.
- primary h. defective gonadal development or function, or both, due to abnormality or loss of the gonad itself.
- secondary h. SYN: hypogonadotropic h..
- h. with anosmia failure of sexual development secondary to inadequate secretion of pituitary gonadotrophins, associated with anosmia due to agenesis of the olfactory lobes of the brain. Autosomal dominant [MIM*147950], autosomal recessive [MIM*244200], and X-linked recessive [MIM*308700] forms exist; the X-linked form is caused by mutation in the Kallmann gene (KAL1) on Xp. SYN: Kallmann syndrome.

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hy·po·go·nad·ism -'gō-.nad-.iz-əm n
1) functional incompetence of the gonads esp. in the male with subnormal or impaired production of hormones and germ cells
2) an abnormal condition (as Klinefelter's syndrome) involving gonadal incompetence

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n.
impaired function of the testes or ovaries, causing absence or impairment of the secondary sexual characteristics.

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hy·po·go·nad·ism (hi″po-goґnad-iz-əm) a condition resulting from abnormally decreased gonadal function, with retardation of growth, sexual development, and secondary sex characters; see hypo-orchidism, hypo-ovarianism, and eunuchoidism. Called also hypogenitalism.

Medical dictionary. 2011.

Look at other dictionaries:

  • Hypogonadism — Classification and external resources ICD 10 E28..3,E29..1,E23..0 …   Wikipedia

  • hypogonadism — n. impaired function of the gonads (testes or ovaries), causing absence or inadequate development of the secondary sexual characteristics. This may be due to a disorder of the gonads or to lack of secretion of the pituitary gonadotrophins… …   The new mediacal dictionary

  • hypogonadism — noun incompetence of the gonads (especially in the male with low testosterone); results in deficient development of secondary sex characteristics and (in prepubertal males) a body with long legs and a short trunk • Hypernyms: ↑incompetence •… …   Useful english dictionary

  • hypogonadism — /huy peuh goh na diz euhm, gon a /, n. Pathol. 1. diminished hormonal or reproductive functioning in the testes or the ovaries. 2. a manifestation of this, as delayed pubescence or Klinefelter s syndrome. Also, hypogonadia /huy poh goh nad ee… …   Universalium

  • hypogonadism — noun A defect of the reproductive system that results in lack of function of the gonads (ovaries or testes) …   Wiktionary

  • hypogonadism — n. reduced activity of the testes or ovaries (Medicine) …   English contemporary dictionary

  • hypogonadism — [ˌhʌɪpə(ʊ) gəʊnadɪz(ə)m] noun Medicine reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries). Derivatives hypogonadal adjective hypogonadic noun & adjective …   English new terms dictionary

  • hypogonadism — hy·po·gonad·ism …   English syllables

  • hypogonadism — hy•po•gon•ad•ism [[t]ˌhaɪ pəˈgoʊ næˌdɪz əm, ˈgɒn æ [/t]] n. Pathol. 1) pat diminished hormonal or reproductive functioning in the testes or the ovaries 2) pat a manifestation of this, as delayed pubescence • Etymology: 1915–20 …   From formal English to slang

  • hypogonadotropic hypogonadism — hypogonadism due to lack of gonadotropin secretion; either luteinizing hormone or follicle stimulating hormone or both may be deficient; it may also be caused by lack of secretion of gonadotropin releasing hormone, as in Kallmann syndrome. Called …   Medical dictionary


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