- Decreased quantity of the gamma fraction of serum globulin; sometimes used loosely to denote decreased quantity of immunoglobulins in general; associated with increased susceptibility to pyogenic infections. SYN: hypogammaglobinemia.- secondary h. SYN: secondary immunodeficiency.- transient h. of infancy a type of primary immunodeficiency that occurs in infants of both sexes, usually before the sixth month of life, probably resulting from immaturity of lymphoid tissue. SYN: transient agammaglobulinemia.- X-linked h., X-linked infantile h. a congenital, primary immunodeficiency characterized by decreased numbers (or absence) of circulating B lymphocytes with corresponding decrease in immunoglobulins of the five classes; associated with marked susceptibility to infection by pyogenic bacteria (notably, pneumococci and Haemophilus influenzae) beginning after loss of maternal antibodies; X-linked recessive inheritance caused by mutation in the Bruton tyrosine kinase gene (BTK) on Xq.- X-linked h. with growth hormone deficiency h. combined with a reduced number of B cells; characterized by short stature, delayed puberty, and recurrent infections.
* * *hy·po·gam·ma·glob·u·lin·emia or chiefly Brit hy·po·gam·ma·glob·u·lin·ae·mia -.gam-ə-.gläb-yə-lə-'nē-mē-ə n a deficiency of gamma globulins and esp. antibodies in the blood also a state of immunological deficiency characterized by thishy·po·gam·ma·glob·u·lin·emic or chiefly Brit hy·po·gam·ma·glob·u·lin·ae·mic -'nē-mik adj
* * *hy·po·gam·ma·glob·u·lin·emia (hi″po-gam″ə-glob″u-lĭ-neґme-ə) abnormally low levels of all classes of immunoglobulins in the blood; see also agammaglobulinemia, dysglobulinemia, and immunodeficiency.
Medical dictionary. 2011.
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Hypogammaglobulinemia — Classification and external resources ICD 10 D80.0 D80.1 ICD 9 … Wikipedia
hypogammaglobulinemia — noun A type of immune disorder characterised by a reduction in all types of gamma globulins … Wiktionary
hypogammaglobulinemia — hy·po·gam·ma·glob·u·li·ne·mia … English syllables
hypogammaglobulinemia — A condition in which the level of immunoglobulins (antibodies) in the blood is low and the risk of infection is high … English dictionary of cancer terms
hypogammaglobulinemia — noun an abnormally low concentration of gamma globulin in the blood and increased risk of infection • Hypernyms: ↑immunodeficiency … Useful english dictionary
Transient hypogammaglobulinemia of infancy — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD10|D|80|7|d|80 ICD9 = ICD9|279.09 ICDO = OMIM = MedlinePlus = eMedicineSubj = ped eMedicineTopic = 2280 MeshID = Transient hypogammaglobulinemia of infancy is a form of… … Wikipedia
physiologic hypogammaglobulinemia — a normal period of hypogammaglobulinemia seen in all infants at about 5â€“6 months of age as the level of transplacentally acquired maternal immunoglobulins declines before endogenous immunoglobulin synthesis rises to normal levels … Medical dictionary
transient hypogammaglobulinemia of infancy — prolongation of the normal physiologic hypogammaglobulinemia of infancy caused by delayed development of endogenous immunoglobulin production and associated with increased susceptibility to infections … Medical dictionary
X-linked hypogammaglobulinemia — X linked infantile hypogammaglobulinemia see under agammaglobulinemia … Medical dictionary
acquired hypogammaglobulinemia — common variable immunodeficiency … Medical dictionary