3-hydroxyacyl-CoA dehydrogenase

β-Hydroxyacyl dehydrogenase; an enzyme catalyzing the oxidation of an l-3-hydroxyacyl-CoA to a 3-ketoacyl-CoA with the concomitant reduction of NAD+; one of the enzymes of the β oxidation of fatty acid s. SYN: β-ketohydrogenase, β-ketoreductase.

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3-hy·droxy·ac·yl-CoA de·hy·dro·gen·ase (hi-drok″se-aґsəl ko-aґ de-hiґdro-jən-ās) [EC 1.1.1.35] an enzyme of the oxidoreductase class that catalyzes the oxidation at the C-3 of L-hydroxyacyl coenzyme A to form ketoacyl coenzyme A, using NAD+ as an electron acceptor. The reaction is one of the steps in fatty acid oxidation.

Medical dictionary. 2011.

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