hydrocortisone

A reduction product (at C-11) of cortisone; a steroid hormone secreted by the adrenal cortex (the active hormone secreted in the greatest quantity by the adrenals) and the most potent of the naturally occurring glucocorticoids in humans; an antiinflammatory agent. SYN: cortisol.
- h. acetate an ester of h. with similar actions and uses as h.. SYN: cortisol acetate.
- h. cyclopentylpropionate an ester of h..
- h. cypionate the cyclopentanepropionic ester of cortisone, for oral administration.
- h. hydrogen succinate a form of h. administered intravenously.
- h. sodium phosphate an anti-inflammatory agent for intravenous or intramuscular administration.
- h. sodium succinate a very soluble ester salt of h. (cortisol), used parenterally in the management of emergencies resulting from acute adrenal insufficiency.

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hy·dro·cor·ti·sone -'kȯrt-ə-.sōn, -.zōn n cortisol esp cortisol used pharmaceutically

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n.
a pharmaceutical preparation of the steroid hormone cortisol. Hydrocortisone is used in the treatment of adrenal failure (Addison's disease) and inflammatory, allergic, and rheumatic conditions (including rheumatoid arthritis, colitis, and eczema). It may be given by mouth, by injection, or in the form of a cream, ointment, or eye or ear drops. Possible side-effects of hydrocortisone therapy include peptic ulcers, bone and muscle damage, suppression of growth in children, and the signs of Cushing's syndrome.

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hy·dro·cor·ti·sone (hi″dro-korґtĭ-sōn) [USP] the name given to cortisol when used as a pharmaceutical, applied to both the natural hormone and the same substance produced synthetically; it has life-maintaining and blood pressure–sustaining properties and also has limited mineralocorticoid activity. The official preparation and its salts are used primarily for their antiinflammatory and immunosuppressant properties, in the treatment of a wide variety of disorders, including allergic disorders, dermatologic disorders, adrenocortical insufficiency and other endocrine disorders, gastrointestinal disorders, hematologic disorders, musculoskeletal disorders, ophthalmologic disorders, respiratory disorders, rheumatic disorders, neoplasms, and shock. The base is administered orally, rectally, or topically.

Medical dictionary. 2011.

Look at other dictionaries:

  • hydrocortisone — [ idrokɔrtizɔn ] n. f. • 1959; de hydro et cortisone ♦ Biochim. Hormone corticosurrénale prescrite principalement comme médicament anti inflammatoire. ● hydrocortisone nom féminin Substance médicamenteuse destinée à suppléer à un déficit en… …   Encyclopédie Universelle

  • hydrocortisone — ☆ hydrocortisone [hī΄drəkôrt′ə sōn΄, hī΄drə kôrt′əzōn΄ ] n. the principal carbohydrate regulating corticosteroid, C21H30O5, in humans, with effects similar to cortisone …   English World dictionary

  • hydrocortisone — cortisol cortisol n. a steroid hormone ({C21H30O5}) active in carbohydrate and protein metabolism; called also {hydrocortisone}. It is used in medicine as an antiinflammatory agent Syn: hydrocortisone. [WordNet 1.5] …   The Collaborative International Dictionary of English

  • hydrocortisone — n. a pharmaceutical preparation of the steroid hormone cortisol. Hydrocortisone is used in the treatment of adrenal failure (Addison s disease), shock, and inflammatory, allergic, and rheumatic conditions (including rheumatoid arthritis, colitis …   The new mediacal dictionary

  • Hydrocortisone — Cortisol Cortisol Représentation moléculaire du Cortisol Général No CAS …   Wikipédia en Français

  • hydrocortisone — kortizolis statusas T sritis chemija apibrėžtis Steroidinis antinksčių žievės hormonas. atitikmenys: angl. cortisol; hydrocortisone rus. гидрокортизон; кортизол ryšiai: sinonimas – hidrokortizonas …   Chemijos terminų aiškinamasis žodynas

  • hydrocortisone — noun Date: 1951 cortisol; especially cortisol used pharmaceutically …   New Collegiate Dictionary

  • hydrocortisone — (= cortisol; 17 hydroxy corticosterone) Powerful corticosteroid produced by cells of the zona reticularis in the adrenal gland. Has potent anti inflammatory effects …   Dictionary of molecular biology

  • hydrocortisone — /huy dreuh kawr teuh zohn , sohn /, n. 1. Biochem. a steroid hormone, C21H30O5, of the adrenal cortex, active in carbohydrate and protein metabolism. 2. Pharm. Also called cortisol. a powerful anti inflammatory drug, C21H30O5, used in the… …   Universalium

  • hydrocortisone — noun a) A steroid hormone, produced by the adrenal cortex, that regulates the metabolism of carbohydrates and maintains blood pressure. b) A synthetic version of this hormone used to treat Addisons disease and other conditions …   Wiktionary

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