1. A grainlike particle; a granulation; a minute discrete mass. 2. A very small pill, usually gelatin or sugar coated, containing a drug to be given in a small dose. 3. A colony of the bacterium or fungus causing a disease or simply colonizing the tissues of the patient. In immunocompromised patients the differentiation is difficult. 4. A small particle that can be seen by electron microscopy; contains stored material. [L. granulum, dim. of granum, grain]
- α granules large, rodlike, or filamentous granules found in several types of cells, especially platelets where they are the most numerous type of g.; contain secretory proteins, including fibrinogen, fibronectin, fibrospondin, von Willebrand factor (collectively known as adhesive proteins) and other proteins (platelet factor 4, platelet-derived growth factor, coagulation factor V, etc.).
- acidophil g. a g. that stains with an acid dye such as eosin. SYN: oxyphil g..
- acrosomal g. the single glycoprotein rich g. within an acrosomal vesicle, which results from the coalescence of proacrosomal granules.
- alpha g. a g. of an alpha cell that was named as the first of several kinds or because it was acidophilic.
- Altmann g. 1. SYN: fuchsinophil g.. 2. SYN: mitochondrion.
- amphophil g. a g. that stains with both acid and basic dyes.
- argentaffin granules granules that reduce silver ions from an ammoniac silver nitrate staining solution.
- azurophil g. a g. that stains a reddish purple color with an azure dye; such granules are seen in dry smears of certain mature and developing blood cells, and are membrane-bound primary lysosomes containing enzymes. SYN: kappa g..
- basal g. SYN: basal body.
- basophil g. a g. that stains readily with a basic dye.
- Bensley specific granules granules in the cells of the islands of Langerhans in the pancreas.
- beta g. a g. of a beta cell.
- Birbeck g. SYN: Langerhans g..
- Bollinger granules 1. relatively small, but frequently microscopically visible, pale yellow or yellow-white granules observed in the granulomatous lesion, or the exudate, in botryomycosis; the granules consist of irregular aggregates or colonizations of Gram-positive cocci, usually staphylococci; 2. term sometimes incorrectly used synonymously with Bollinger bodies.
- chromatic g. SYN: chromophil g. (2).
- chromophil g. 1. any readily stainable g.; 2. a g. of chromophil (Nissl) substance. SYN: chromatic g..
- chromophobe granules granules that do not stain or stain poorly with the ordinary dyes; such granules are present in some cells in the anterior lobe of the pituitary.
- cone g. nucleus of a retinal cell connecting with one of the cones.
- Crooke granules lumpy masses of basophilic material in the basophil cells of the anterior lobe of the pituitary, associated with Cushing disease, or following the administration of ACTH.
- delta g. a g. of a delta cell.
- elementary g. a particle of blood dust, or hemoconia.
- eosinophil g. a g. that stains with eosin.
- Fordyce granules SYN: Fordyce spots, under spot.
- fuchsinophil g. a g. that has an affinity for fuchsin. SYN: Altmann g. (1).
- glycogen g. glycogen occurring in cells as beta granules which average about 300 Å in diameter, or as alpha granules which are aggregates measuring 900 Å of smaller particles.
- iodophil g. a g. that stains brown with iodine; found in many of the polymorphonuclear leukocytes in pneumonia, erysipelas, scarlet fever, and various other acute diseases.
- juxtaglomerular granules osmophilic secretory granules present in the juxtaglomerular cells, thought to contain renin.
- kappa g. SYN: azurophil g..
- keratohyalin granules irregularly shaped basophilic granules in the cells of the stratum granulosum of the epidermis.
- Langerhans g. a small tennis racket-shaped membrane-bound g. with characteristic cross-striated internal ultrastructure; first reported in Langerhans cells of the epidermis. SYN: Birbeck g..
- Langley granules granules in serous secreting cells.
- membrane-coating g. SYN: keratinosome.
- metachromatic granules 1. granules that stain a color different from that of the dye used; SEE ALSO: metachromasia. 2. term sometimes used as a synonym for volutin.
- mucinogen granules granules that produce mucin, as in cells of the salivary glands and in the gastric and intestinal mucosae.
- Neusser granules tiny basophilic granules sometimes observed in an indistinct zone about the nucleus of a leukocyte.
- neutrophil g. a g. stainable with the neutral component of stains, e.g., the Romanovsky-type blood stains.
- Nissl granules SYN: Nissl substance.
- oxyphil g. SYN: acidophil g..
- Palade g. SYN: ribosome.
- proacrosomal granules small carbohydrate-rich granules appearing in vesicles of the Golgi apparatus of spermatids; they coalesce into a single acrosomal g. contained within an acrosomal vesicle.
- prosecretion granules granules in the cytoplasm of a cell indicative of a preliminary step in the formation of a secretory product.
- rod g. the nucleus of a retinal cell connecting with one of the rods.
- Schüffner granules SYN: Schüffner dots, under dot.
- secretory g. a membrane-bound particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.
- seminal g. one of the minute granular bodies present in the semen.
- specific granules the distinctive granules of basophilic, eosinophilic, and neutrophilic leukocytes, as opposed to their nonspecific azurophilic granules.
- volutin granules SYN: volutin.
- Zimmermann g. obsolete term for platelet.

* * *

gran·ule 'gran-(.)yü(ə)l n
1 a) a little grain or small particle esp one of a number of particles forming a larger unit
b) a small sugar-coated pill
2) a clump of actinomycetes in a lesion

* * *

gran·ule (granґūl) [L. granulum] 1. a small particle or grain, as the small beadlike masses of tissue formed on the surface of wounds, or the insoluble nonmembranous particles found in cytoplasm. 2. a small pill made from sucrose.

Medical dictionary. 2011.


Look at other dictionaries:

  • granule — [ granyl ] n. m. • 1842; bas lat. granulum, dimin. de granum « grain » ♦ Didact. Petit grain. Pharm. Petite pilule. Granules homéopathiques. ● granule nom masculin (latin granulum) Petit grain d une matière quelconque. N …   Encyclopédie Universelle

  • granulé — granule [ granyl ] n. m. • 1842; bas lat. granulum, dimin. de granum « grain » ♦ Didact. Petit grain. Pharm. Petite pilule. Granules homéopathiques. ● granule nom masculin ( …   Encyclopédie Universelle

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  • granule — granulė statusas T sritis fizika atitikmenys: angl. granule vok. Körnchen, n rus. гранула, f pranc. granule, f …   Fizikos terminų žodynas

  • Granule — Gran ule (gr[a^]n [ u]l), n. [L. granulum, dim. of granum grain: cf. F. granule. See {Grain} a kernel.] A little grain; a small particle; a pellet. [1913 Webster] …   The Collaborative International Dictionary of English

  • Granule — (von lat. granulum, Körnchen) steht für das einzelne Element einer körnigen Oberfläche, siehe Granulation die Konvektionszellen auf der Sonne und anderen Fixsternen, siehe Granulation (Astronomie) eine dunkle Pore an der Sonnenoberfläche, siehe… …   Deutsch Wikipedia

  • granulé — granulé, ée (gra nu lé, lée) part. passé de granuler. 1°   Formé de petits grains. Marbre granulé. 2°   Terme d histoire naturelle. Qui renferme ou porte des granulations, ou qui en a l apparence …   Dictionnaire de la Langue Française d'Émile Littré

  • granule — 1650s, from Fr. granule or directly from L.L. granulum small grain, dim. of L. granum grain (see CORN (Cf. corn) (1)) …   Etymology dictionary

  • granule — granulė statusas T sritis chemija apibrėžtis Specialiai suformuotas medžiagos gabalėlis. atitikmenys: angl. grain; granule; pellet; prill rus. гранула …   Chemijos terminų aiškinamasis žodynas

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  • granulė — grãnulė dkt. Máltą mė̃są sumaišýkite su išbrinki̇̀ntomis sòjos grãnulėmis …   Bendrinės lietuvių kalbos žodyno antraštynas

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