glomerulosclerosis

Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes. SYN: glomerular sclerosis. [glomerulus + G. sklerosis, hardness]
- diabetic g. proteinuria and ultimately, renal failure occuring in long standing diabetes and characterized by rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening and increased mesangial matrix. SYN: intercapillary g..
- focal segmental g. segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis.
- intercapillary g. SYN: diabetic g..

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glo·mer·u·lo·scle·ro·sis -(y)ə-.lō-sklə-'rō-səs n, pl -ro·ses -.sēz nephrosclerosis involving the renal glomeruli

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glo·mer·u·lo·scle·ro·sis (glo-mer″u-lo-sklə-roґsis) fibrosis and scarring with senescence of the renal glomeruli.

Medical dictionary. 2011.

Look at other dictionaries:

  • glomerulosclerosis — f. nefrol. Alteración del glomérulo renal que conduce a la insuficiencia renal por pérdida de su capacidad funcional. Puede ser resultado de procesos degenerativos o inflamatorios. Medical Dictionary. 2011. glomeruloscler …   Diccionario médico

  • Glomerulosclerosis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 33012 ICD10 = ICD9 = ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Glomerulosclerosis refers to a hardening of the glomerulus in the kidney.More specifically, it can… …   Wikipedia

  • glomerulosclerosis — noun A hardening of the glomerulus in the kidney …   Wiktionary

  • glomerulosclerosis — glo·mer·u·lo·sclerosis …   English syllables

  • glomerulosclerosis — glämer(y)ə(ˌ)lō+, glə| noun Etymology: New Latin, from glomerul + sclerosis : nephrosclerosis involving the glomeruli …   Useful english dictionary

  • glomerulosclerosis intercapilar — Trastorno caracterizado por la degeneración de los glomérulos renales. Se asocia con la diabetes y frecuentemente produce albuminuria, edema nefrótico, hipertensión e insuficiencia renal. Diccionario Mosby Medicina, Enfermería y Ciencias de la… …   Diccionario médico

  • Focal segmental glomerulosclerosis — DiseaseDisorder infobox Name = Focal segmental glomerulosclerosis ICD10 = N00 N08 (with .1 suffix) ICD9 = ICD9|581.1 OMIM = 603278 OMIM mult = OMIM2|603965 OMIM2|607832 MedlinePlus =000478 eMedicineSubj = med eMedicineTopic = 2944 MeshID =… …   Wikipedia

  • focal glomerulosclerosis — focal segmental glomerulosclerosis the occurrence of focal sclerosing lesions of the renal glomeruli, marked by proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another disease, such as heroin …   Medical dictionary

  • diabetic glomerulosclerosis — the characteristic microscopic changes seen in a diabetic kidney after many years of progressive damage. * * * intercapillary g …   Medical dictionary

  • intercapillary glomerulosclerosis — a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse or nodular lesions; the nodular lesions are known as Kimmelstiel Wilson lesions. Symptoms include albuminuria, nephrotic edema,… …   Medical dictionary

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