- Disease, Whipple
- A form of intestinal malabsorption (an inability to absorb nutrients from the intestine) described in 1907 by the pathologist and Nobel laureate George H. Whipple in a medical missionary who first developed arthritis and then weight loss, cough, fever, diarrhea, hypotension (low blood pressure), abdominal swelling, increased skin pigmentation, and severe anemia. The disease has been discovered to be due to a previously unknown type of bacteria, now named Tropheryma whippelii, which was reported in the year 2000 to have been grown in the laboratory, opening the way for the development of a simple blood test to diagnose the disease. The disease is treated with antibiotics. Some patients relapse. They may need long-term (even life-long) treatment.
Medical dictionary. 2011.
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Whipple's disease — also Whipple disease n a rare malabsorption syndrome that is caused by an actinomycetous fungus (Tropheryma whippelli) in the mucous membrane of the intestine, that affects primarily the small intestine but becomes more generalized affecting esp … Medical dictionary
Whipple-Krankheit — Klassifikation nach ICD 10 K90.8 Sonstige intestinale Malabsorption Whipple Krankheit M14.8* Arthropathien bei sonstigen näher bezeichneten, anderenorts klassifizierten Krankheiten Arthritis … Deutsch Wikipedia
Whipple disease — A form of intestinal malabsorption (an inability to absorb nutrients from the intestine) described in 1907 by the pathologist and Nobel laureate George H. Whipple in a medical missionary who first developed arthritis and then weight loss, cough,… … Medical dictionary
Whipple's disease — a rare disease, occurring only in males, in which absorption of digested food in the intestine is reduced. As well as symptoms and signs of malabsorption there is usually skin pigmentation and arthritis. Diagnosis is made by jejunal biopsy;… … The new mediacal dictionary
Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… … Medical dictionary
Whipple — Allen O., U.S. surgeon, 1881–1963. See W. operation. George H., U.S. pathologist and Nobel laureate, 1878–1976. See W. disease … Medical dictionary
George Whipple — Infobox Scientist name = George Whipple birth date = August 28, 1878 birth place = Ashland, New Hampshire death date = February 1, 1976 death place = residence = citizenship = nationality = United States ethnicity = field = medicine work… … Wikipedia