Disease, Whipple


Disease, Whipple
A form of intestinal malabsorption (an inability to absorb nutrients from the intestine) described in 1907 by the pathologist and Nobel laureate George H. Whipple in a medical missionary who first developed arthritis and then weight loss, cough, fever, diarrhea, hypotension (low blood pressure), abdominal swelling, increased skin pigmentation, and severe anemia. The disease has been discovered to be due to a previously unknown type of bacteria, now named Tropheryma whippelii, which was reported in the year 2000 to have been grown in the laboratory, opening the way for the development of a simple blood test to diagnose the disease. The disease is treated with antibiotics. Some patients relapse. They may need long-term (even life-long) treatment.

Medical dictionary. 2011.

Look at other dictionaries:

  • Whipple procedure — A type of surgery used to treat pancreatic cancer. The head of the pancreas, the duodenum, a portion of the stomach, and other nearby tissues are removed. The Whipple procedure is named for Allen O. Whipple, an American surgeon, 1881 1963 (not… …   Medical dictionary

  • Whipple's disease — Classification and external resources Low magnification micrograph of Whipple s disease showing the characteristic foamy appearing infiltrate of the lamina propria. Duodenal biopsy. H& …   Wikipedia

  • Whipple — may refer to:PeopleFamily name*Abraham Whipple (1733–1819), American revolutionary naval commander *Allen Whipple (1881–1963), American surgeon, eponym of the Whipple procedure (Pancreaticoduodenectomy) and Whipple s triad *Amiel Weeks Whipple… …   Wikipedia

  • Whipple's disease — also Whipple disease n a rare malabsorption syndrome that is caused by an actinomycetous fungus (Tropheryma whippelli) in the mucous membrane of the intestine, that affects primarily the small intestine but becomes more generalized affecting esp …   Medical dictionary

  • Whipple-Krankheit — Klassifikation nach ICD 10 K90.8 Sonstige intestinale Malabsorption Whipple Krankheit M14.8* Arthropathien bei sonstigen näher bezeichneten, anderenorts klassifizierten Krankheiten Arthritis …   Deutsch Wikipedia

  • Whipple disease — A form of intestinal malabsorption (an inability to absorb nutrients from the intestine) described in 1907 by the pathologist and Nobel laureate George H. Whipple in a medical missionary who first developed arthritis and then weight loss, cough,… …   Medical dictionary

  • Whipple's disease — a rare disease, occurring only in males, in which absorption of digested food in the intestine is reduced. As well as symptoms and signs of malabsorption there is usually skin pigmentation and arthritis. Diagnosis is made by jejunal biopsy;… …   The new mediacal dictionary

  • Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary

  • Whipple — Allen O., U.S. surgeon, 1881–1963. See W. operation. George H., U.S. pathologist and Nobel laureate, 1878–1976. See W. disease …   Medical dictionary

  • George Whipple — Infobox Scientist name = George Whipple birth date = August 28, 1878 birth place = Ashland, New Hampshire death date = February 1, 1976 death place = residence = citizenship = nationality = United States ethnicity = field = medicine work… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.