DES


DES
: Diethylstilbestrol, the earliest synthetic (man-made) form of a hormone in the estrogen class. DES was once widely prescribed to prevent miscarriages and premature births. Its usage was standard practice in the 1950s and 1960s. Millions of women received the drug. Girls whose mothers were given DES during pregnancy ("DES daughters") were discovered to be at increased risk for being born with malformations of the reproductive organs and to face elevated rates of infertility and miscarriages themselves. DES daughters were also found to be at increased risk for cancer of the cervix and vagina, specifically for developing clear-cell adenocarcinoma of the vagina and cervix, a relatively uncommon type of cancer, at an early age. In 2000, DES daughters were reported to be 3-5 times more likely to have the more common forms of cervical cancer than women whose mothers did not take DES. DES sons are predisposed to testicular abnormalities, such as abnormally small testes) and failure of the testes to descend into the scrotum, which increases the risk of testicular cancer. All women and men who believe they may have been exposed to DES before birth should inform their doctor of their exposure so that they may be appropriately examined and monitored. DES is still available for prescription in the US. According to the package insert, DES "is indicated for the treatment of" (and we quote): {{}}"Breast cancer (palliation only) in appropriately selected women and men with metastatic disease" and "Prostatic cancer — palliative therapy of advanced disease."
* * *
Abbreviation for diethylstilbestrol.
* * *
Danish Enoxaparin Study; data encryption standard; dementia rating scale; dermal-epidermal separation; descendant [UMLS]; desmin; dialysis encephalopathy syndrome; diethylstilbestrol; diffuse esophageal spasm; disequilibrium syndrome; dissociative experience scale; doctor's emergency service; drug-eluding stent

* * *

DES .dē-(.)ē-'es n DIETHYLSTILBESTROL

* * *

diethylstilbestrol.

Medical dictionary. 2011.

Look at other dictionaries:

  • Des — steht für: Data Encryption Standard, ein symmetrischer Verschlüsselungsalgorithmus Detached Eddy Simulation, ein Verfahren zur numerischen Lösung dreidimensionaler Strömungsmodelle Diethylstilbestrol, ein Arzneistoff aus der Gruppe der… …   Deutsch Wikipedia

  • Des Vœux — could mean: Sir George William Des Vœux, a British colonial officer Dr. Henry Antoine Des Voeux, a scientist who first coined the term smog Des Voeux Road, road in Hong Kong named after the colonial officer Des Voeux Island is a member of the… …   Wikipedia

  • DES — steht für: Data Encryption Standard, ein symmetrischer Verschlüsselungsalgorithmus Delivered Ex Ship (dt.: Geliefert ab Schiff), eine internationale Handelsklausel nach den Incoterms Detached Eddy Simulation, ein Verfahren zur numerischen Lösung… …   Deutsch Wikipedia

  • DES — may refer to: Computing Data Encryption Standard DirectShow Editing Services, an Application Programming Interface Medical Diethylstilbestrol, a synthetic estrogen and the origin of the phrase DES daughter DES gene, which encodes the Desmin… …   Wikipedia

  • DÈS — préposition de temps et de lieu Depuis, à partir de. Dès cette époque là, ou Dès là (ce dernier a vieilli). Dès l enfance. Dès hier. Dès Orléans. Dès sa source.   Dès lors, Dès ce moment là, dès ce temps là. Je vis bien dès lors où il voulait en… …   Dictionnaire de l'Academie Francaise, 7eme edition (1835)

  • DES-X — In cryptography, DES X (or DESX) is a variant on the DES (Data Encryption Standard) block cipher intended to increase the complexity of a brute force attack using a technique called key whitening. The original DES algorithm was specified in 1976… …   Wikipedia

  • Dés — László Dés [ˈlaːsloː ˈdeːʃ] (* 9. Januar 1954 in Budapest) ist ein ungarischer Jazz Saxophonist und Komponist. Dés besuchte von 1960 bis 1968 die Musikschule Zoltán Kodály. Von 1963 bis 1971 absolvierte er eine Klavierausbildung. Danach studierte …   Deutsch Wikipedia

  • des- — prefix Etymology: French dés , from Old French des more at de de 6 especially before vowels < desoxy > …   New Collegiate Dictionary

  • Des — (ре бемоль) первая ступень (тоника) в диатонических гаммах Des dur, Des moll; вторая ступень ces dur и малоупотребительной ces moll; третья ступень в гамме b moll; четвертая ступень (суб доминанта) в гаммах as dur, as moll; пятая ступень… …   Энциклопедический словарь Ф.А. Брокгауза и И.А. Ефрона

  • DES — noun Date: 1970 diethylstilbestrol …   New Collegiate Dictionary

  • DES — *  Mot qui tient lieu, par contraction, de la préposition De et de l article pluriel Les. Voyez la préposition DE …   Dictionnaire de l'Academie Francaise, 7eme edition (1835)


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.