dehydrogenase

Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors), which are thus reduced; most of the oxidative enzymes (oxidoreductases, EC class 1) perform their oxidations in this manner.
- aerobic d. an enzyme (usually a metalloflavoenzyme) catalyzing the transfer of hydrogen from some metabolite to oxygen, forming hydrogen peroxide in the process; e.g., xanthine oxidase and others in several sub-subclasses ( e.g., EC 1.1.3, 1.2.3, 1.7.3, 1.8.3, 1.10.3).
- anaerobic d. an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule ( e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenases, isocitrate dehydrogenases, and others in EC class 1, excluding those listed under aerobic d..
- α-keto acid d. See α-keto acid d..
- Robison ester d. SYN: glucose-6-phosphate d..

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de·hy·dro·ge·nase .dē-(.)hī-'dräj-ə-.nās, (')dē-'hī-drə-jə-, -.nāz n an enzyme that accelerates the removal of hydrogen from metabolites and its transfer to other substances see SUCCINATE DEHYDROGENASE

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n.

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de·hy·dro·gen·ase (de-hiґdro-jən″ās) an enzyme of the oxidoreductase class [EC 1] that catalyzes the transfer of hydrogen or electrons from a donor, which becomes oxidized, to an acceptor compound, which becomes reduced. Dehydrogenases are usually designated according to the hydrogen donor.

Medical dictionary. 2011.

Look at other dictionaries:

  • dehydrogenase — ☆ dehydrogenase [dē hī′drə jən ās΄, dē΄hī drä′jə nās΄ ] n. [ DE + HYDROGEN + ASE] any oxidoreductase enzyme that acts as a catalyst, in chemical reactions involving oxidation, by the removal of hydrogen …   English World dictionary

  • Dehydrogenase — A dehydrogenase (also called DHO in the literature) is an enzyme that oxidises a substrate by a reduction reaction that transfers one or more hydrides (H−) to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.… …   Wikipedia

  • Dehydrogenase — Eine Dehydrogenase ist ein Enzym, das sein Substrat durch Abspaltung von Wasserstoffatomen oxidiert. Dehydrogenasen gehören zur Gruppe I (Oxidoreduktasen) der EC Klassifikation. Der abgespaltene Wasserstoff wird auf Cosubstrate wie NAD+ oder FAD… …   Deutsch Wikipedia

  • dehydrogenase — noun Etymology: International Scientific Vocabulary Date: 1923 an enzyme that accelerates the removal of hydrogen from metabolites and its transfer to other substances compare succinate dehydrogenase …   New Collegiate Dictionary

  • Dehydrogenase — De|hy|d|ro|ge|na|se [↑ de u. ↑ Hydrogenase], die; , n: veraltetes Syn.: Dehydrase: ein Enzym (↑ Oxidoreduktase), das die Ablösung von 2 Wasserstoff Atomen aus org. Verb. (↑ Oxidation) u. anschließend (als Hydrogenase) die Übertragung von H2 auf… …   Universal-Lexikon

  • dehydrogenase — dehidrogenazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis dviejų vandenilio atomų atskilimą nuo substrato. atitikmenys: angl. dehydrogenase rus. дегидрогеназа …   Chemijos terminų aiškinamasis žodynas

  • dehydrogenase — (|)dē+ noun Etymology: International Scientific Vocabulary de + hydrogenase : any of various enzymes that accelerate the removal of hydrogen from metabolites and its transfer to other substances (as diphosphopyridine nucleotide) and thus play an… …   Useful english dictionary

  • dehydrogenase — Enzyme that oxidizes a substrate by transferring hydrogen to an acceptor that is either NAD+/NADP+ or a flavin enzyme …   Dictionary of molecular biology

  • dehydrogenase — /dee huy dreuh jeuh nays , nayz /, n. Biochem. an oxidoreductase enzyme that catalyzes the removal of hydrogen. [1920 25; DEHYDROGEN(ATE) + ASE] * * * …   Universalium

  • dehydrogenase — noun Any of several enzymes that catalyze the removal of hydrogen (a proton) from biological compounds …   Wiktionary

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