Cox-1 (cyclooxygenase-1)


Cox-1 (cyclooxygenase-1)
This protein acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers (called prostaglandins). The prostaglandins work within certain cells responsible for inflammation and other functions. In the stomach, for example, they promote the production of the natural mucus lining which protects the inner stomach. Because the common antiinflammatory drugs (like aspirin, ibuprofen and naproxen) block the action of Cox-1, they can reduce inflammation, but they can also decrease the natural stomach protective mucus lining and lead to stomach upset, intestinal bleeding, and ulcers.

Medical dictionary. 2011.

Look at other dictionaries:

  • Cox-2 (cyclooxygenase-2) — This protein acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers (called prostaglandins). Some of these messengers are responsible for promoting inflammation. When Cox 2 activity is blocked,… …   Medical dictionary

  • cyclooxygenase — noun either of two related enzymes that control the production of prostaglandins and are blocked by aspirin • Syn: ↑Cox • Hypernyms: ↑enzyme • Hyponyms: ↑cyclooxygenase 1, ↑Cox 1, ↑cyclooxygenase 2, ↑C …   Useful english dictionary

  • Cyclooxygenase — COX redirects here. For other meanings, see Cox (disambiguation). prostaglandin endoperoxide synthase Identifiers EC number 1.14.99.1 CAS number …   Wikipedia

  • COX-2 — Cyclooxygenase 2 Kalottenmodell der COX 2 nach PDB  …   Deutsch Wikipedia

  • Cyclooxygenase 2 — Kalottenmodell der COX 2 nach PDB  …   Deutsch Wikipedia

  • COX-2 inhibitor — COX 2 selective inhibitor is a form of non steroidal anti inflammatory drug (NSAID) that directly targets COX 2, an enzyme responsible for inflammation and pain. Targeting selectivity for COX 2 reduces the risk of peptic ulceration, and is the… …   Wikipedia

  • COX-1 — Cyclooxygenase 1 Oberflächenmodell nach PDB  …   Deutsch Wikipedia

  • Cyclooxygenase-2 — Vorhandene Strukturdaten: PDB  …   Deutsch Wikipedia

  • Cyclooxygenase-1 — Vorhandene Strukturdaten …   Deutsch Wikipedia

  • COX-inhibiting nitric oxide donator — COX inhibiting nitric oxide donators (CINODs), also known as NO NSAIDs, are a new class of non steroidal anti inflammatory drug (NSAID) developed with the intention of providing greater safety than existing NSAIDs. These compounds were first… …   Wikipedia


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