- A major metabolite of nicotine with a long half life. It is a breakdown product of nicotine. Cotinine is widely used as a quantitative biomarker of cigarette smoking. It is an objective measurement and provides more accurate prevalence rates than smoking histories or from counting the number of cigarettes smoked per day. A study reported in 2001 by the US Centers for Disease Control (the CDC) showed the blood level of cotinine in non-smoking adults had fallen 75% in the past decade. This drop was interpreted as due to indoor smoking bans and decreased smoking.
* * *One of the major detoxication products of nicotine; eliminated rapidly and completely by the kidneys. [anagram of nicotine]
* * *co·tin·ine 'kōt-ən-.ēn, -.īn n an alkaloid C10H12N2O that is the principal metabolite of nicotine and is widely used as an indicator of recent exposure to nicotine
* * *co·ti·nine (koґtĭ-nēn) the major urinary metabolite of nicotine.
Medical dictionary. 2011.
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Cotinine — Not to be confused with cotinin. Cotinine Systematic (IUPAC) name (5S) 1 methyl 5 (3 pyridyl)pyrrolidin 2 one Clinical data … Wikipedia
cotinine — ˈkōd.ənˌēn, ˌīn noun ( s) Etymology: probably anagram of nicotine : an alkaloid C10H12N2O that is the principal metabolite of nicotine and is widely used as an indicator of recent exposure to nicotine * * * cotinine /kotˈə nēn/ noun A nicotine… … Useful english dictionary
cotinine — noun Etymology: probably anagram of nicotine Date: 1893 an alkaloid C10H12N2O that is the principal metabolite of nicotine … New Collegiate Dictionary
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