- Colony-stimulating factor
- A laboratory-made agent similar to a substance in the body that stimulates the production of blood cells. Treatment with colony-stimulating factors (CSFs) can help the blood- forming tissue recover from the effects of chemotherapy and radiation therapy. The CSFs include granulocyte colony-stimulating factors (G-CSF) and granulocyte-macrophage colony-stimulating factors (GM-CSF).
* * *
col·o·ny-stim·u·lat·ing factor -.stim-yə-.lāt-iŋ- n any of several glycoproteins that promote the differentiation of stem cells esp. into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture see GRANULOCYTE COLONY-STIMULATING FACTOR, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR, INTERLEUKIN-3, MACROPHAGE COLONY-STIMULATING FACTOR* * *
one of a group of substances (haemopoietic growth factors or hormones) that are produced in the bone marrow and stimulate the production of specific blood cells. Genetically engineered granulocyte colony-stimulating factor (G-CSF) stimulates neutrophil production and also limits bone marrow toxicity from chemotherapy.
Medical dictionary. 2011.
Look at other dictionaries:
Colony-stimulating factor — Colony stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate… … Wikipedia
colony-stimulating factor — A substance that stimulates the production of blood cells. Colony stimulating factors include granulocyte colony stimulating factor (G CSF), granulocyte macrophage colony stimulating factor (GM CSF), and promegapoietin … English dictionary of cancer terms
colony-stimulating factor — noun : any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture abbreviation CSF; see granulocyte colony… … Useful english dictionary
colony-stimulating factor — CSF one of a group of substances (haemopoietic growth factors or hormones) that are produced in the bone marrow and stimulate the production of specific blood cells. Genetically engineered granulocyte colony stimulating factor (G CSF) stimulates… … The new mediacal dictionary
colony-stimulating factor — noun Date: 1969 any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture … New Collegiate Dictionary
colony-stimulating factor — Cytokines involved in the maturation of various leucocyte, macrophage, monocyte lines … Dictionary of molecular biology
colony-stimulating factor-1 — See CSF 1 … Dictionary of molecular biology
Colony stimulating factor 1 receptor — Rendering based on PDB 2I0V … Wikipedia
Macrophage colony-stimulating factor — Colony stimulating factor 1 (macrophage) PDB rendering based on 1hmc … Wikipedia
Granulocyte colony-stimulating factor — Not to be confused with granulocyte macrophage colony stimulating factor. Colony stimulating factor 3 (granulocyte) Crystal structure of 3 molecules of human G CSF. From PDB … Wikipedia