clavulanic acid

A beta-lactam structurally related to the penicillins that inactivate β-lactamase enzymes in penicillin-resistant organisms; usually used in combination with penicillins to enhance and broaden the spectrum of the penicillins.

* * *

clav·u·lan·ic acid .klav-yə-.lan-ik- n a beta-lactam antibiotic C8H9NO5 produced by a bacterium of the genus Streptomyces (S. clavuligerus) that is a beta-lactamase inhibitor and is usu. used in the form of its clavulanate salt of potassium esp. in combination with amoxicillin see AUGMENTIN

* * *

a drug that interferes with the penicillinase that inactivate beta-lactam antibiotic, such as amoxicillin or ticarcillin. Combined with the antibiotic, clavulanic acid can overcome drug resistance.

Medical dictionary. 2011.

Look at other dictionaries:

  • Clavulanic acid — Systematic (IUPAC) name …   Wikipedia

  • clavulanic acid — a drug that interferes with the penicillinases that inactivate beta lactam antibiotics, such as amoxicillin or ticarcillin. Combined with the antibiotic, clavulanic acid can overcome drug resistance …   The new mediacal dictionary

  • clavulanic acid — noun An inhibitor of enzymatic hydrolysis that is added to penicillin antibiotics …   Wiktionary

  • Amoxicillin/clavulanic acid — Combination of Amoxicillin Penicillin antibiotic Clavulanic acid Beta lactamase inhibitor Clinical data Pregnancy cat. B(US) Legal status …   Wikipedia

  • Кислота Клавулановая (Clavulanic Acid) — вещество, взаимодействующее с пенициллиназами, которое инактивирует большинство антибиотиков пенициллинового ряда (например, амоксициллин). В сочетании с такими антибиотиками, как аугментин (Augmentin) или тиментин (Timentin), клавулановая… …   Медицинские термины

  • clavulanic — adjective Of or pertaining to clavulanic acid or its derivatives …   Wiktionary

  • Clavam — clavulanic acid A clavam is a molecule similar to a penam, but with an oxygen substituted for the sulfur.[1] Thus, they are also known as oxapenams. An example is clavulanic acid …   Wikipedia

  • КИСЛОТА КЛАВУЛАНОВАЯ — (clavulanic acid) вещество, взаимодействующее с пенициллиназами, которое инактивирует большинство антибиотиков пенициллинового ряда (например, амоксициллин). В сочетании с такими антибиотиками, как аугментин (Augmentin) или тиментин (Timentin),… …   Толковый словарь по медицине

  • Beta-lactamase — Beta lactamases are enzymes (EC number|3.5.2.6) produced by some bacteria and are responsible for their resistance to beta lactam antibiotics like penicillins, cephalosporins, cephamycins, ertapenems and carbapenems. These antibiotics have a… …   Wikipedia

  • Amoxicillin — Systematic (IUPAC) name (2S,5R,6R) 6 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.