thrombin time

(TT), thrombin clotting time the time required for plasma fibrinogen to form thrombin: exogenous thrombin is added to citrated plasma and the time to clot formation is measured; it is prolonged with abnormalities of fibrinogen and in the presence of heparin or of fibrin/fibrinogen degradation products.

Medical dictionary. 2011.

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  • Prothrombin time — A clotting test, the prothrombin time is done to test the integrity of part of the clotting scheme. The prothrombin time is commonly used as a method of monitoring the accuracy of blood thinning treatment (anticoagulation) with COUMADIN.… …   Medical dictionary

  • Direct thrombin inhibitor — Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin. Some are in clinical use, while others are undergoing clinical development. Several… …   Wikipedia

  • Ecarin clotting time — (ECT) is a laboratory test used to monitor anticoagulation during treatment with hirudin, an anticoagulant medication which was originally isolated from leech saliva. Ecarin, the primary reagent in this assay, is derived from the venom of the saw …   Wikipedia

  • prothrombin time — PT the time taken for blood clotting to occur in a sample of blood to which calcium and thromboplastin have been added. A prolonged PT (compared with a control sample) indicates a deficiency of coagulation factors, which – with calcium and… …   The new mediacal dictionary

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