acute chest syndrome

a complex of symptoms seen in patients with sickle cell disease, often due to a bacterial infection or to infarction of lung tissue; characteristics include severe chest pain, dyspnea, tachypnea, fever, excessive leukocytosis, pulmonary edema, and sometimes petechiae on the chest or conjunctivae as well as fat emboli. Death may result from severe pulmonary complications.

Medical dictionary. 2011.

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