cholinesterase

One of a family of enzymes capable of catalyzing the hydrolysis of acylcholines and a few other compounds. In mammals, found in white matter of brain, liver, heart, pancreas, and serum. It is also found in cobra venom. SEE ALSO: acetylcholinesterase. SYN: choline esterase II, nonspecific c., “s”-type c..
- “e”-type c. SYN: acetylcholinesterase. [“e” as in erythrocyte]
- nonspecific c. SYN: c..
- “s”-type c. SYN: c.. [“s” as in serum]
- true c. SYN: acetylcholinesterase.

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cho·lin·es·ter·ase .kō-lə-'nes-tə-.rās, -.rāz n
1) ACETYLCHOLINESTERASE
2) an enzyme that hydrolyzes choline esters and that is found esp. in blood plasma called also pseudocholinesterase

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n.
an enzyme that breaks down a choline ester into its choline and acid components. The term usually refers to acetylcholinesterase, which breaks down the neurotransmitter acetylcholine into choline and acetic acid. It is found in all cholinergic nerve junctions, where it rapidly destroys the acetylcholine released during the transmission of a nerve impulse so that subsequent impulses may pass. Other cholinesterases are found in the blood and other tissues.

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cho·lin·es·ter·ase (CHS) (ko″lin-esґtər-ās) [EC 3.1.1.8] an enzyme of the hydrolase class that catalyzes the cleavage of the acyl group from various esters of choline, including acetylcholine, and some related compounds (cf. acetylcholinesterase). The enzyme occurs primarily in the serum, liver, and pancreas; determination of enzyme activity is used to test liver function, succinylcholine sensitivity, and whether organophosphate insecticide poisoning has occurred. Called also choline esterase II (unspecific), pseudocholinesterase (PCE), and serum c. (SChE).

Medical dictionary. 2011.

Look at other dictionaries:

  • cholinestérase — [ kɔlinɛsteraz ] n. f. • 1935; angl. cholinesterase (1932); de choline et estérase ♦ Biochim. Enzyme qui hydrolyse l acétylcholine en choline et acide acétique, et joue un rôle important dans le fonctionnement du système nerveux. ● cholinestérase …   Encyclopédie Universelle

  • Cholinesterase — Cholinestérase L acétylcholinestérase est la principale enzyme du genre cholinestérase. En biochimie une cholinestérase est une enzyme qui catalyse la réaction d hydrolyse d un ester de la choline (acétylcholine, butyrylcholine) en c …   Wikipédia en Français

  • cholinesterase — [kō΄lənes′tər ās΄] n. [< CHOLINE + ESTERASE] an enzyme which hydrolyzes a choline ester; esp., acetylcholine, which converts to choline and acetic acid, thus canceling a nerve impulse transmission …   English World dictionary

  • Cholinesterase — acetylcholinesterase (Yt blood group) Diagram of Pacific electric ray acetylcholinesterase. From PDB 1EA5 …   Wikipedia

  • Cholinesterase — Cholinesterasen (ChE) sind Enzyme, die Cholin Ester spalten. Sie sind im Stoffwechsel von vielzelligen Tieren unverzichtbar zum Abbau dieser Stoffe, insbesondere des Acetylcholins, einem Neurotransmitter. Es gibt zwei Cholinesterasen.… …   Deutsch Wikipedia

  • Cholinestérase — L acétylcholinestérase est la principale enzyme du genre cholinestérase. En biochimie une cholinestérase est une enzyme qui catalyse la réaction d hydrolyse d un ester de la choline (acétylcholine, butyrylcholine) en choline et en acide acétiqu …   Wikipédia en Français

  • cholinesterase — noun Date: 1932 1. acetylcholinesterase 2. an enzyme that hydrolyzes choline esters and that is found especially in blood plasma called also pseudocholinesterase …   New Collegiate Dictionary

  • cholinesterase — /koh leuh nes teuh rays , rayz , kol euh /, n. Biochem. an enzyme, found esp. in the heart, brain, and blood, that hydrolyzes acetylcholine to acetic acid and choline. [1930 35; CHOLINE + ESTERASE] * * * …   Universalium

  • cholinesterase — noun An enzyme, in muscles, nerves etc, that catalyzes the hydrolysis of acetylcholine …   Wiktionary

  • Cholinesterase — Cholin|estera̱se [↑Cholin und ↑Esterase]: Acetylcholin spaltendes Enzym im Nervengewebe …   Das Wörterbuch medizinischer Fachausdrücke

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