sulfite oxidase

sul·fite ox·i·dase (sulґfīt okґsĭ-dās) [EC 1.8.3.1] an enzyme of the oxidoreductase class that catalyzes the final reaction in the degradation of sulfur-containing amino acids, oxidizing sulfite to sulfate; it also oxidizes and detoxifies sulfite and sulfur dioxide from exogenous sources. It is a mitochondrial molybdoenzyme that transfers electrons to cytochrome c via its b5 heme. Deficiency of enzyme activity, due to defect in the enzyme protein or to molybdenum cofactor deficiency (q.v.), results in progressive neurologic abnormalities, lens dislocation, and mental retardation.

Medical dictionary. 2011.

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  • Sulfite oxidase — protein Name = sulfite oxidase caption = width = HGNCid = 11460 Symbol = SUOX AltSymbols = EntrezGene = 6821 OMIM = 606887 RefSeq = NM 000456 UniProt = P51687 PDB = ECnumber = Chromosome = 12 Arm = q Band = 13.13 LocusSupplementaryData = Sulfite… …   Wikipedia

  • Sulfite dehydrogenase — In enzymology, a sulfite dehydrogenase (EC number|1.8.2.1) is an enzyme that catalyzes the chemical reaction:sulfite + 2 ferricytochrome c + H2O ightleftharpoons sulfate + 2 ferrocytochrome c + 2 H+The 3 substrates of this enzyme are sulfite,… …   Wikipedia

  • sulfite — A salt of sulfurous acid; elevated in cases of molybdenum cofactor deficiency. s. dehydrogenase an oxidoreductase catalyzing the reaction of s. with 2ferricytochrome c and water to sulfate and 2ferrocytochrome c. s …   Medical dictionary

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Oxidoreductase — In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen or electron donor) to another (the oxidant, also called the hydrogen or electron acceptor). This… …   Wikipedia

  • Dihydrolipoamide dehydrogenase — PDB rendering based on 1zy8 …   Wikipedia

  • Microbial metabolism — is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce. Microbes use many different types of metabolic strategies and species can often be differentiated from each other based on metabolic… …   Wikipedia

  • Molybdenum — niobium ← molybdenum → technetium Cr ↑ Mo ↓ W …   Wikipedia

  • Molybdopterin — Identifiers CAS number 73508 07 3  …   Wikipedia

  • Molybdenum cofactor deficiency — Classification and external resources OMIM 252150 DiseasesDB 29905 eMedicine …   Wikipedia

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