- Raynaud phenomenon); there are also fibrotic degenerative changes in body organs such as the heart, lungs, kidneys, and gastrointestinal tract. It may be confined to the face and hands for long periods or may progress, spread diffusely, and become generalized. Called also diffuse s. and systemic sclerosis. See also CREST syndrome.
Systemic scleroderma with characteristic tense shiny skin and fixed clawlike position of the fingers caused by acro-osteolysis and flexion contractures.
Medical dictionary. 2011.
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