A blue, copper-containing α-globulin of blood plasma, with a molecular weight of about 122,000 and 6 or 7 atoms of copper per molecule; involved in copper transport and regulation, and can reduce O2 directly without known intermediates; has ferroxidase and polyamine oxidase activities. C. is absent in congenital Wilson disease. [L. caeruleus, dark blue]

* * *

ce·ru·lo·plas·min sə-.rü-lō-'plaz-mən n a blue copper-binding serum oxidase that is deficient in Wilson's disease and that may catalyze the conversion of ferrous iron in tissues to ferric iron

* * *

ce·ru·lo·plas·min (sə-roo″lo-plazґmin) a deep blue, copper-containing α2-globulin with a single subunit, occurring in blood plasma. It is an acute phase protein, has ferroxidase activity, and binds 6 or 7 Cu2+ ions per molecule, functioning in transport and maintenance of tissue levels of copper. It can also oxidize other unsaturated compounds. Ceruloplasmin is absent in Wilson disease.

Medical dictionary. 2011.

Look at other dictionaries:

  • Ceruloplasmin — (ferroxidase) PDB rendering based on 1kcw …   Wikipedia

  • ceruloplasmin — ceruloplasmin. См. α2 глобулин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • ceruloplasmin — ceruloplazminas statusas T sritis chemija apibrėžtis Kraujo plazmos baltymas, turintis Cu²⁺. atitikmenys: angl. ceruloplasmin rus. церулоплазмин …   Chemijos terminų aiškinamasis žodynas

  • ceruloplasmin — sə̇¦rülō¦plazmə̇n, ¦ser(y)əl noun ( s) Etymology: International Scientific Vocabulary cerulo (from Latin caeruleus dark blue) + plasma + in; probably originally formed in Swedish : a blue copper binding serum oxidase that is deficient in Wilson s …   Useful english dictionary

  • ceruloplasmin — noun Etymology: International Scientific Vocabulary cerulo (from Latin caeruleus) + plasma + 1 in Date: circa 1952 a blue copper binding serum oxidase that is deficient in Wilson s disease …   New Collegiate Dictionary

  • ceruloplasmin — A blue copper containing dehydrogenase protein (135 kD) found in serum (200 500 m g/ml). Apparently involved in copper detoxification and storage, and possibly also in mopping up excess oxygen radicals or superoxide anions …   Dictionary of molecular biology

  • ceruloplasmin — /seuh rooh leuh plaz min/, n. Biochem. a serum glycoprotein involved in the storage and transport of copper and iron. [1950 55; < NL cerulo , comb. form repr. L caeruleus (see CERULEAN, O ) + PLASM(A) + IN2] * * * …   Universalium

  • ceruloplasmin — noun A blue metalloprotein that contains copper; it acts as a ferroxidase in association with transferrin …   Wiktionary

  • ceruloplasmin — ce·ru·lo·plas·min …   English syllables

  • Ceruloplasmin deficiency — Lack of the protein ceruloplasmin from the blood and accumulation of iron in the pancreas, liver and brain, causing diabetes and progressive nervous system degeneration with the tremors and gait abnormalities characteristic of Parkinson disease.… …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.