Dale reaction

an in vitro test for anaphylactic sensitization in the guinea pig: a small amount of the antigen added to a tissue bath in which is immersed the excised uterine horn (smooth muscle) of an anaphylactically sensitized guinea pig causes contraction of the sensitized uterine muscle. Called also Schultz-Dale r. NOTE: Schultz employed intestinal muscle; Dale used uterine muscle from virgin guinea pigs.

Medical dictionary. 2011.

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  • Dale reaction (phenomenon) — (dāl) [Sir Henry Hallett Dale, British physiologist, pharmacologist, and Nobel prize winner, 1875–1968 ] see under reaction …   Medical dictionary

  • Schultz-Dale reaction — shu̇ltz dāl n a reaction of anaphylaxis carried out in vitro with isolated tissues Schultz Werner (1878 1947) German internist. Schultz is best known for his classic description of agranulocytosis in 1922. He did his research on anaphylaxis… …   Medical dictionary

  • schultz-dale reaction — ˈshu̇]ltsˈdā(ə)l , ˈshü] noun Usage: usually capitalized S&D Etymology: after Werner Schultz b1878 German physician and Sir Henry Hallett Dale died 1968 English physiologist : a reaction of anaphylaxis carried out in vitro with isolated tissues… …   Useful english dictionary

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  • reaction — 1. The response of a muscle or other living tissue or organism to a stimulus. 2. The color change effected in litmus and certain other organic pigments by contact with substances such as acids or alkalies; also the property that such substances… …   Medical dictionary

  • Dale — Sir Henry Hallett, English physiologist and Nobel laureate, 1875–1968. See D. reaction, D. Feldberg law, Schultz D. reaction. * * * disability adjusted life expectancy; Drug Abuse Law Enforcement …   Medical dictionary

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