carbidopa

A dopa decarboxylase inhibitor which does not enter the brain used in conjunction with levodopa in the treatment of Parkinson disease to reduce L-dopa doses and reduce side effect s.

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car·bi·do·pa .kär-bə-'dō-pə n a drug C10H14N2O4·H2O that inhibits decarboxylation of L-dopa in tissues outside the brain and that is administered with, L-dopa in the treatment of Parkinson's disease to increase the amount of, L-dopa available for transport to the brain

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car·bi·do·pa (kahr″bĭ-doґpə) [USP] an inhibitor of the decarboxylation of peripheral levodopa to dopamine, which does not penetrate the central nervous system. When given with levodopa, carbidopa produces higher brain concentrations of dopamine with lower doses of levodopa, thus lessening the side effects seen with higher doses. It is used orally, in conjunction with levodopa, as an antiparkinsonian agent.

Medical dictionary. 2011.

Look at other dictionaries:

  • carbidopa — inhibidor de la decarboxilasa que no atraviesa la barrera hematoencefálica y, por tanto, solo actúa periféricamente. Se utiliza en el tratamiento de la enfermedad de Parkinson, conjuntamente con la levodopa estructura química [véase… …   Diccionario médico

  • Carbidopa — Strukturformel Allgemeines Freiname Carbidopa Andere Namen …   Deutsch Wikipedia

  • Carbidopa — drugbox IUPAC name = (2 S ) 3 (3,4 dihydroxyphenyl) 2 hydrazinyl 2 methyl propanoic acid CAS number = 28860 95 9 ATC prefix = ATC suffix = ATC supplemental = PubChem = 34359 DrugBank = APRD00160 C=10 | H=14 | N=2 | O=4 molecular weight = 226.229… …   Wikipedia

  • carbidopa — n.; see levodopa …   The new mediacal dictionary

  • Carbidopa/levodopa — Combination of Agonist Levodopa Enzyme inhibitor Carbidopa Clinical data MedlinePlus a601068 …   Wikipedia

  • 5-Hydroxytryptophan — Not to be confused with serotonin (5 hydroxytryptamine, 5 HT). 5 Hydroxytryptophan …   Wikipedia

  • Entacapone — Systematic (IUPAC) name (2E) 2 cyano 3 (3,4 dihydroxy 5 nitrophenyl) N,N diethylprop 2 enamide Clinical data Trade names …   Wikipedia

  • Parkinsonmittel — sind Arzneimittel, die zur Behandlung der Parkinson Krankheit verwendet werden. Die Parkinson Krankheit ist dadurch charakterisiert, dass es in den Basalganglien des Gehirns einen relativen Mangel an Dopamin gibt, der durch das Absterben… …   Deutsch Wikipedia

  • L-dopa — Nombre (IUPAC) sistemático …   Wikipedia Español

  • 5-Hidroxitriptófano — Esta página o sección está siendo traducida del idioma inglés a partir del artículo 5 hydroxytryptophan, razón por la cual puede haber lagunas de contenidos, errores sintácticos o escritos sin traducir. Puedes colaborar con Wikipedia …   Wikipedia Español


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