Koch phenomenon

if a guinea pig that has been previously infected with tuberculosis organisms is reinjected intracutaneously, the skin over the injected area undergoes necrosis; a superficial ulcer develops and heals quickly, and infection of regional lymph nodes is retarded. The phenomenon demonstrates development of ability to localize tubercle bacilli, which is the principle underlying tuberculin tests.

Medical dictionary. 2011.

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  • koch phenomenon — ˈkȯk , ˈkȯḵ , ˈkōk , ˈkäk noun Usage: usually capitalized K Etymology: after Robert Koch died 1910 German bacteriologist : the response of a tuberculous animal to reinfection with tubercle bacilli marked by necrotic lesions that develop… …   Useful english dictionary

  • Koch phenomenon postulate tuberculin — (kawk) [R. Koch] see under phenomenon, postulate, and tuberculin …   Medical dictionary

  • Koch's phenomenon — also Koch phenomenon n the response of a tuberculous animal to reinfection with tubercle bacilli marked by necrotic lesions that develop rapidly and heal quickly and caused by hypersensitivity to products of the tubercle bacillus …   Medical dictionary

  • Koch's bacillus — kōks , käch əz or Koch bacillus kōk , käch n a bacillus of the genus Mycobacterium (M. tuberculosis) that causes human tuberculosis Koch kȯk (Heinrich Hermann) Robert (1843 1910) German bacteriologist. Koch is usually hailed as the founder of… …   Medical dictionary

  • Koch — Robert, German bacteriologist and Nobel laureate, 1843–1910. See K. bacillus, K. law, K. old tuberculin, K. phenomenon, K. postulates, under postulate, K. Weeks bacillus. Walter, German surgeon, *1880. See K. node, K. triangle. * * * (kawk)… …   Medical dictionary

  • phenomenon — 1. A symptom; an occurrence of any sort, whether ordinary or extraordinary, in relation to a disease. 2. Any unusual fact or occurrence. [G. phainomenon, fr. phaino, to cause to appear] adhesion p. a p. manifested by the adherence of antigen… …   Medical dictionary

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  • Ernst Nolte — (born 11 January 1923) is a German historian and philosopher, whose primary interest is the comparative study of Nazism, Fascism and Communism. His nationalistic views of German history have often proved controversial.… …   Wikipedia

  • literature — /lit euhr euh cheuhr, choor , li treuh /, n. 1. writings in which expression and form, in connection with ideas of permanent and universal interest, are characteristic or essential features, as poetry, novels, history, biography, and essays. 2.… …   Universalium

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