3-oxoacid CoA-transferase

3-oxo·ac·id CoA-trans·fer·ase (ok″so-asґid ko-aґ transґfər-ās) [EC] an enzyme of the transferase class that catalyzes the shift of coenzyme A (CoA) from succinyl CoA to acetoacetic acid to form acetoacetyl CoA; the reaction is part of a mechanism by which free β-hydroxybutyrate can be converted to acetyl CoA and used as fuel. The enzyme is present in muscle and nerve tissue but absent from liver, and it can also act on some related keto acids. Called also 3-ketoacid CoA transferase.

Medical dictionary. 2011.

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  • 3-oxoacid CoA-transferase — In enzymology, a 3 oxoacid CoA transferase (EC number| is an enzyme that catalyzes the chemical reaction:succinyl CoA + a 3 oxo acid ightleftharpoons succinate + a 3 oxoacyl CoAThus, the two substrates of this enzyme are succinyl CoA and… …   Wikipedia

  • 3-oxoacid-CoA transferase — An enzyme catalyzing the reversible conversion of acetoacetyl CoA and succinate into succinyl CoA and acetoacetate; malonyl CoA can substitute for succinyl CoA and a few other 3 oxo acids for the acetoacetate; an important …   Medical dictionary

  • 3-ketoacid CoA transferase — 3 ke·to·ac·id CoA trans·fer·ase (ke″to asґid ko aґ transґfər ās) 3 oxoacid CoA transferase …   Medical dictionary

  • 3-ketoacid-CoA transferase — SYN: 3 oxoacid CoA transferase …   Medical dictionary

  • OXCT1 — 3 oxoacid CoA transferase 1 PDB rendering based on 1m3e …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • acetoacetyl-succinic thiophorase — SYN: 3 oxoacid CoA transferase …   Medical dictionary

  • Dihydrolipoyl transacetylase — dihydrolipoyllysine residue acetyltransferase Atomic structure of a single subunit of dihydrolipoyl transacetylase from Azotobacter vinelandii that makes up the structural core of the pyruvate dehydrogenase multienzyme complex.[1] …   Wikipedia

  • metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism …   Universalium

  • Dihydrolipoyl-Transacylase — Masse/Länge Primärstruktur 421 Aminosäuren …   Deutsch Wikipedia

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