- A key intermediate in the synthesis of ketone bodies, of steroids, and of farnesyl and geranyl derivatives. SYN: 3-hydroxy- 3-methylglutaryl-CoA.- β-hydroxy- β-methylglutaryl- lyase an enzyme, found primarily in liver and rumen epithelium that catalyzes the formation of acetyl-CoA and acetoacetate from β-hydroxy-β-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis.- β-hydroxy- β-methylglutaryl- reductase an enzyme that catalyzes the rate-limiting step of cholesterol biosynthesis : β-hydroxy-β-methylglutaryl-CoA + 2NADPH + 2H+ → (R)-mevalonate + 2NADP+ + CoA.
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3-hydroxy-3-methylglutaryl-CoA — SYN: β hydroxy β methylglutaryl CoA … Medical dictionary
3-hydroxy-3-methylglutaryl-CoA lyase deficiency — Infobox Disease Name = PAGENAME Caption = HMG CoA DiseasesDB = 29826 ICD10 = ICD9 = ICDO = OMIM = 246450 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = C0080473 hydroxy 3 methylglutaryl CoA lyase deficiency also referred to as HMG CoA… … Wikipedia
3-hydroxy-3-methylglutaryl-CoA lyase — protein Name = 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase (hydroxymethylglutaricaciduria) caption = width = HGNCid = 5005 Symbol = HMGCL AltSymbols = EntrezGene = 3155 OMIM = 246450 RefSeq = NM 000191 UniProt = P35914 PDB = ECnumber =… … Wikipedia
3-hydroxy-3-méthylglutaryl-coenzyme A — Structure de la 3 hydroxy 3 méthylglutaryl coenzyme A Général Synonymes … Wikipédia en Français
3-hydroxy-3-methylglutaryl — 3 hy·droxy 3 meth·yl·glu·ta·ryl (hi drok″se meth″əl glooґtə rəl) a radical of 3 hydroxy 3 methylglutaric acid; the thioester it forms with coenzyme A, 3 hydroxy 3 methylglutaryl CoA, is an intermediate in the catabolism … Medical dictionary
5-hydroxy-3-methylglutaryl-coenzyme A reductase — noun a liver enzyme that is responsible for producing cholesterol • Syn: ↑HMG CoA reductase • Hypernyms: ↑reductase … Useful english dictionary
Hydroxymethylglutaryl-CoA synthase — In enzymology, a hydroxymethylglutaryl CoA synthase (EC number|220.127.116.11) is an enzyme that catalyzes the chemical reaction:acetyl CoA + H2O + acetoacetyl CoA ightleftharpoons (S) 3 hydroxy 3 methylglutaryl CoA + CoAThe 3 substrates of this enzyme … Wikipedia
HMG-CoA-Reduktase — Stäbchenmodell des Dimers mit Kalotten: Coenzym A (blau), β Hydroxy β methyl glutarylsäure (rot) und NADP (gr … Deutsch Wikipedia
Hydroxymethylglutaryl-CoA reductase (NADPH) — In enzymology, a hydroxymethylglutaryl CoA reductase (NADPH) (EC number|18.104.22.168) is an enzyme that catalyzes the chemical reaction:(R) mevalonate + CoA + 2 NADP+ ightleftharpoons (S) 3 hydroxy 3 methylglutaryl CoA + 2 NADPH + 2 H+The 3… … Wikipedia
Hydroxymethylglutaryl-CoA hydrolase — In enzymology, a hydroxymethylglutaryl CoA hydrolase (EC number|22.214.171.124) is an enzyme that catalyzes the chemical reaction:(S) 3 hydroxy 3 methylglutaryl CoA + H2O ightleftharpoons CoA + 3 hydroxy 3 methylglutarateThus, the two substrates of this … Wikipedia