blockade

1. Intravenous injection of large amounts of colloidal dyes or other substances in order to block reticuloendothelial cells ( e.g., phagocytosis is temporarily prevented). 2. Receptor b., blocking the effect of a hormone at the cell surface. 3. Arrest of peripheral nerve conduction or transmission at autonomic synaptic junctions, autonomic receptor sites, or myoneural junctions by a drug. 4. The occupation of receptors by an antagonist so that usual agonists are relatively ineffective.
- adrenergic b. selective inhibition by a drug of the responses of effector cells to adrenergic sympathetic nerve impulses (sympatholytic) and to epinephrine and related amines (adrenolytic).
- cholinergic b. 1. inhibition by a drug of nerve impulse transmission at autonomic ganglionic synapses (ganglionic b.), at postganglionic parasympathetic effector cells ( e.g., by atropine), and at myoneural junctions (myoneural b.); 2. the inhibition of a cholinergic agent.
- ganglionic b. inhibition of nerve impulse transmission at autonomic ganglionic synapses by drugs such as nicotine or hexamethonium.
- myoneural b. inhibition of nerve impulse transmission at myoneural junctions by a drug such as curare.
- narcotic b. the use of drugs to inhibit the effects of narcotic substances, as with naloxone.
- sympathetic b. interruption of transmission in sympathetic ganglia or conduction of impulses in pre- or postganglionic sympathetic nerve fibers.
- virus b. the interference of one virus by another, either attenuated or unrelated.

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block·ade blä-'kād n
1 a) interruption of normal physiological function (as transmission of nerve impulses) of a cellular receptor, tissue, or organ
b) inhibition of a physiologically active substance (as a hormone)
2) the process of reducing the phagocytic capabilities of the reticuloendothelial system by loading it with harmless material (as India ink or lampblack) which engages its cells in phagocytosis and prevents them from reacting to new antigenic material compare BLOCKING ANTIBODY
blockade vt, block·ad·ed; block·ad·ing to subject to blockade

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block·ade (blok-ādґ) 1. receptor blockade, the blocking of the effect of a hormone or neurotransmitter at a cell-surface receptor by a pharmacologic antagonist bound to the receptor. 2. in histochemistry, a chemical reaction that by modifying certain chemical groups blocks a specific staining method. 3. regional anesthesia.

Medical dictionary. 2011.

Synonyms:
(as ports, so as to prevent egress or ingress), , , , (as of a port), ,


Look at other dictionaries:

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  • blockade — n Blockade, siege are comparable when denoting an attempt of a belligerent force to break down the resistance of the enemy by preventing egress or ingress of men or entrance of supplies over a considerable period of time. Blockade is used chiefly …   New Dictionary of Synonyms

  • Blockade — Block*ade , n. [Cf. It. bloccata. See {Block}, v. t. ] 1. The shutting up of a place by troops or ships, with the purpose of preventing ingress or egress, or the reception of supplies; as, the blockade of the ports of an enemy. [1913 Webster]… …   The Collaborative International Dictionary of English

  • blockade — [blä kād′] n. [ BLOCK + ADE] 1. a shutting off of a port or region of a belligerent state by the troops or ships of the enemy in order to prevent passage in or out in time of war 2. any blocking action designed to isolate another nation and cut… …   English World dictionary

  • Blockade — Block*ade , v. t. [imp. & p. p. {Blockaded}; p. pr. & vb. n. {Blockading}.] 1. To shut up, as a town or fortress, by investing it with troops or vessels or war for the purpose of preventing ingress or egress, or the introduction of supplies. See… …   The Collaborative International Dictionary of English

  • blockade — ► NOUN ▪ an act of sealing off a place to prevent goods or people from entering or leaving. ► VERB ▪ set up a blockade of. ● run a blockade Cf. ↑run a blockade …   English terms dictionary

  • Blockade — (franz. Blocus, engl. Blockade, Blocking), die Absperrung eines feindlichen Ortes oder Bezirks vom Verkehr und namentlich vom Handelsverkehr durch eine kriegführende Macht. Hiernach fällt unter den Begriff der B. im weitern Sinn auch die… …   Meyers Großes Konversations-Lexikon

  • blockade — I (barrier) noun bar, barricade, block, blockage, bottleneck, cordon, curb, impediment, obsessio, obsidio, obstacle, obstruction, stop, stumbling block II (enclosure) noun circumjacence, circumscription, circumvallation, compass, containment,… …   Law dictionary

  • Blockade — Blockade, 1) B. einer Festung, das enge Einschließen einer Festung, um dieselbe von der Verbindung mit Außen abzuschließen; s.u. Festungskrieg; 2) B. eines Hafens, die B. eines feindlichen Hafens wird von Kriegsschiffen, welche vor demselben… …   Pierer's Universal-Lexikon

  • Blockade — Blockade, in der Buchdruckerei jene Stelle im Satze, wo statt des Buchstabenbildes die untere Seite der Letter abgedruckt erscheint, ein in der Mitte getrennter schwarzer Fleck (Fliegenkopf) …   Lexikon der gesamten Technik

  • Blockade — Blockāde, Absperrung eines Hafens oder einer Küste durch Kriegsschiffe. Die B. muß wirksam (effektiv) sein, d.h. die Ein und Ausfahrt und die Landung ständig durch Kriegsschiffe oder auch Landbatterien verhindern. Blockadebrecher, Schiffe, welche …   Kleines Konversations-Lexikon

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