diffuse lymphoma

malignant lymphoma in which the neoplastic cells diffusely infiltrate the entire lymph node, without any definite organized pattern. This category from the Rappaport Classification was replaced by some of the cleaved-cell lymphomas in the Lukes-Collins Classification, by the three subtypes of diffuse lymphomas in the Working Formulation of Non-Hodgkin Lymphomas, and by a variety of specific B- and T-cell neoplasms in the Revised European-American Lymphoma Classification. Called also lymphatic sarcoma and lymphosarcoma.

Medical dictionary. 2011.

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