iodotyrosine deiodinase

io·do·ty·ro·sine de·io·din·ase (i″o-do-tiґro-sēn de-iґo-dĭ-nās) an enzyme that catalyzes the removal of iodine from monoiodotyrosine and diiodotyrosine. The reaction is a step in the conservation of iodine by the thyroid. Congenital deficiency of the enzyme results in severe loss of iodine, resulting in hypothyroidism and goiter. Called also iodotyrosine dehalogenase.

Medical dictionary. 2011.

Look at other dictionaries:

  • Deiodinase — (or iodide peroxidase or Monodeiodinase ) is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones. In general, T4 (thyroxine) is converted into T3 (triiodothyronine) by the deiodinase enzyme in target cells.… …   Wikipedia

  • iodotyrosine dehalogenase — io·do·ty·ro·sine de·hal·o·gen·ase (i o″do tiґro sēn de halґo jən ās) iodotyrosine deiodinase …   Medical dictionary

  • Cytochrome c peroxidase — Cytochrome c peroxidase, or CCP (PDB 2CYP, EC 1.11.1.5) is a water soluble heme containing enzyme of the peroxidase family that takes reducing equivalents from cytochrome c and reduces hydrogen peroxide to water: CCP + H2O2 + 2 ferrocytochrome c… …   Wikipedia

  • Oxidoreductase — In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen or electron donor) to another (the oxidant, also called the hydrogen or electron acceptor). This… …   Wikipedia

  • Myeloperoxidase — drawn from PDB 1D7W …   Wikipedia

  • Diiodotyrosine transaminase — Identifiers EC number 2.6.1.24 CAS number 9033 18 5 …   Wikipedia

  • Dual oxidase 1 — Identifiers Symbols DUOX1; LNOX1; MGC138840; MGC138841; NOXEF1; THOX1 External IDs …   Wikipedia

  • Dual oxidase 2 — Identifiers Symbols DUOX2; LNOX2; NOXEF2; P138 TOX; TDH6; THOX2 External IDs …   Wikipedia

  • goiter — A chronic enlargement of the thyroid gland, not due to a neoplasm, occurring endemically in certain localities, especially regions where glaciation occurred and the soil is low in iodine, and sporadically elsewhere. SYN: struma (1). [Fr. from L.… …   Medical dictionary

  • Congenital hypothyroidism — Classification and external resources ICD 10 E00, E03.0, E03.1 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.