- Candidate gene
- Any gene thought likely to cause a disease. The gene may be a candidate because it is located in a particular chromosome region suspected of being involved in the disease or its protein product may suggest that it could be the disease gene in question.
* * *a DNA sequence that because of its biochemical product, chromosomal location, or other property is considered as a gene of interest; used particularly for a gene considered as potentially causing a particular genetic disorder.
Medical dictionary. 2011.
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candidate gene — candidate gene. См. ген кандидат. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Candidate gene — A candidate gene is a gene, located in a chromosome region suspected of being involved in the expression of a trait such as a disease, whose protein product suggests that it could be the gene in question. A candidate gene can also be identified… … Wikipedia
candidate gene — A gene whose deduced function (on the basis of DNA sequence) suggests that it may be involved in the genetic control of an aspect of phenotype … Glossary of Biotechnology
candidate-gene strategy — An experimental approach in which knowledge of the biochemistry and/or physiology of a trait is used to identify candidate genes. Synonym: functional gene cloning … Glossary of Biotechnology
comparative positional candidate gene — Relates to an indirect means of assigning function to a QTL. Where a QTL has been linked to a marker in one species, and that same marker is linked to a known gene in a model system, inferences may be drawn as to the nature of the QTL … Glossary of Biotechnology
positional candidate gene — A gene known to be located in the same region as a DNA marker that has been shown to be linked to a single locus trait or to a QTL, and whose deduced function suggests that it could be the source of genetic variation in the trait in question … Glossary of Biotechnology
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