ATP citrate lyase

See ATP citrate (pro-3S)-lyase.

* * *

ATP cit·rate ly·ase (sitґrāt liґās) an enzyme of the lyase class that catalyzes the ATP-dependent cleavage of citrate to form oxaloacetate and acetate, the latter then condensing with coenzyme A to form acetyl coenzyme A. The reaction is part of the mechanism by which acetyl coenzyme A produced in the mitochondria from pyruvate can be transported to the cytosol to be used in fatty acid synthesis. In EC nomenclature, called ATP citrate (pro-S) lyase [EC 4.1.3.8]. Called also citrate cleavage enzyme.

Medical dictionary. 2011.

Look at other dictionaries:

  • ATP citrate lyase — protein Name=ATP citrate lyase caption= width= HGNCid=115 Symbol=ACLY AltSymbols= EntrezGene=47 OMIM=108728 RefSeq=NM 001096 UniProt=P53396 PDB= ECnumber=2.3.3.8 Chromosome=17 Arm=q Band=21.2 LocusSupplementaryData=ATP citrate lyase is an enzyme… …   Wikipedia

  • ATP-Citrat-Lyase — Masse/Länge Primärstruktur 1101 Aminosäuren …   Deutsch Wikipedia

  • ATP citrate synthase — In enzymology, an ATP citrate synthase (EC number|2.3.3.8) is an enzyme that catalyzes the chemical reaction:ADP + phosphate + acetyl CoA + oxaloacetate ightleftharpoons ATP + citrate + CoAThe 4 substrates of this enzyme are ADP, phosphate,… …   Wikipedia

  • ATP-Citrat-Synthase — ATP Citrat Lyase Größe 1101 Aminosäuren Struktur Homotetramer Kofaktor Magnesium …   Deutsch Wikipedia

  • Citrate synthase family — Citrate synt cold active citrate synthase Identifiers Symbol Citrate synt Pfam …   Wikipedia

  • Citrate synthase — Identifiers Symbol CS Entrez 1431 HUGO …   Wikipedia

  • Citrate—CoA ligase — Identifiers EC number 6.2.1.18 CAS number 856428 87 0 …   Wikipedia

  • citrate cleavage enzyme — cit·rate cleav·age en·zyme (sitґrāt kleґvij enґzīm) ATP citrate lyase …   Medical dictionary

  • (citrate (pro-3S)-lyase) ligase — In enzymology, a [citrate (pro 3S) lyase] ligase (EC number|6.2.1.22) is an enzyme that catalyzes the chemical reaction:ATP + acetate + [citrate (pro 3S) lyase] (thiol form) ightleftharpoons AMP + diphosphate + [citrate (pro 3S) lyase] (acetyl… …   Wikipedia

  • citrate — A salt or ester of citric acid; used as anticoagulants because they bind calcium ions. c. aldolase SYN: c. lyase. ATP c. (pro 3S) lyase an enzyme that catalyzes the reaction of ATP, c., and coenzyme A to …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.