trefoil factor

(TFF) any of a family of protease-resistant peptides having a three-loop structure consisting of six cysteine residues and three disulfide bonds, expressed throughout the gastrointestinal tract. They promote epithelial cell migration and gastrointestinal wound healing, prevent apoptosis and anoikis, and contribute to mucosal protection; TFF1 is also a tumor suppressor. TFF1 is called also pS2; TFF2, spasmolytic polypeptide or spasmolysin; and TFF3, intestinal trefoil f.

Medical dictionary. 2011.

Look at other dictionaries:

  • Trefoil factor 3 — (intestinal), also known as TFF3, is a human gene.cite web | title = Entrez Gene: TFF3 trefoil factor 3 (intestinal)| url = Cmd=ShowDetailView TermToSearch=7033| accessdate = ] PBB Summary section… …   Wikipedia

  • Trefoil factor 2 — (spasmolytic protein 1), also known as TFF2, is a human gene.cite web | title = Entrez Gene: TFF2 trefoil factor 2 (spasmolytic protein 1)| url = Cmd=ShowDetailView TermToSearch=7032| accessdate =… …   Wikipedia

  • Trefoil factor 1 — Trefoil factor 1, also known as TFF1, is a human gene.cite web | title = Entrez Gene: TFF1 trefoil factor 1| url = Cmd=ShowDetailView TermToSearch=7031| accessdate = ] PBB Summary section title =… …   Wikipedia

  • intestinal trefoil factor — trefoil f. 3 …   Medical dictionary

  • Trefoil knot fold — The trefoil knot fold is a protein fold in which the protein backbone is twisted into a trefoil knot shape. Shallow knots in which the tail of the polypeptide chain only passes through a loop by a few residues are uncommon, but deep knots in… …   Wikipedia

  • spasmolytic polypeptide — trefoil factor 2 …   Medical dictionary

  • pS2 — • trefoil factor 1 …   Dictionary of medical acronyms & abbreviations

  • pS2 — trefoil factor 1 * * * trefoil factor 1 …   Medical dictionary

  • TFF — trefoil family factor [1 3]; tube fed food * * * trefoil factor …   Medical dictionary

  • spasmolysin — spas·mol·y·sin (spaz molґĭ sin) trefoil factor 2 …   Medical dictionary

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