primary complex

1. the combination of a parenchymal pulmonary lesion (Ghon focus or tubercle) and a corresponding lymph node focus, occurring in primary tuberculosis, usually in children; it may undergo cellular necrosis and eventually calcify. Similar lesions may also be associated with other mycobacterial infections and with fungal infections such as histoplasmosis and coccidioidomycosis. Called also Ghon c. and Ranke c. 2. the primary cutaneous lesion at the site of an infection in the skin, such as a chancre in syphilis or cutaneous tuberculosis.

Medical dictionary. 2011.

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