amyotrophic lateral sclerosis–parkinsonism–dementia complex

an autosomal dominant disorder caused by mutation in the TRPM7 gene (locus: 15q21), which encodes a protein that functions as an ion channel and a kinase; it occurs among the Chamorro population of Guam and is characterized by gradually progressing parkinsonism associated with progressive dementia and amyotrophic lateral sclerosis.

Medical dictionary. 2011.

Look at other dictionaries:

  • lytico-bodig disease — [lytico bodig, a local name for the disease, formed from truncations of Sp. paralitico paralytic and bodega small store] amyotrophic lateral sclerosis–parkinsonism–dementia complex …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.