suppressor cells

suppressor T cells differentiated T lymphocytes of the CD8 cells group that suppress antibody synthesis or cell-mediated immunity. They may be activated in response to antigen or to idiotypic determinants present on antibodies and T and B cell antigen receptors and may act either by suppressing activity of helper cells or by inhibiting the differentiation of activated lymphocytes into effector cells. Murine suppressor cells are marked by the Ly-2 and Ly-3 antigens, human suppressor cells by the CD5 and CD8 antigens. Cf. contrasuppressor c's.

Medical dictionary. 2011.

Look at other dictionaries:

  • suppressor cells — suppressor cells. = TS lymphocytes (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • suppressor cells — suppressor cells. См. ТS лимфоциты. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • T-suppressor cells — T cells that express the CD8 transmembrane glycoprotein (CD8+ T cells). They close down the immune response after invading organisms are destroyed. Suppressor T cells are sensitive to high concentrations of circulating lymphokine hormones, and… …   Medical dictionary

  • Myeloid-derived Suppressor Cells — Cellule myeloïde suppressive Les cellules myéloïdes suppressives (Myeloid derived suppressor cells ou MdSC) sont des cellules immunitaires, d origine myéloïde, comme les monocytes, mais dont les propriétés sont immunosuppressives. Chez la souris …   Wikipédia en Français

  • Suppressor-inducer — T cells are a specific subset of T helper cells (CD4(+)) that induce cytotoxic T cells (CD8(+)) to become suppressor cells. Suppressor T cells are also known as T regulatory cells (Fox3p(+)), and reduce inflammation. In this fashion, suppressor… …   Wikipedia

  • suppressor factor — (1) Factors released by T suppressor cells. (2) See suppressor mutation and ochre suppressor, opal suppressor …   Dictionary of molecular biology

  • suppressor — [[t]səpre̱sə(r)[/t]] ADJ: ADJ n Suppressor cells or genes are ones that prevent a cancer from developing or spreading. [MEDICAL] …   English dictionary

  • suppressor T cell — n a T cell that suppresses the immune response of B cells and other T cells to an antigen resulting in tolerance for the antigen by the organism containing the T cell called also suppressor cell, suppressor lymphocyte, suppressor T lymphocyte, T… …   Medical dictionary

  • Suppressor of cytokine signaling 1 — Identifiers Symbols SOCS1; CIS1; CISH1; JAB; SOCS 1; SSI 1; SSI1; TIP3 External IDs …   Wikipedia

  • suppressor t cell — noun or suppressor cell Usage: usually capitalized T : a T cell that suppresses the response of B cells and other T cells to an antigen resulting in tolerance for the antigen by the organism containing the T cell compare helper t cell herein… …   Useful english dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.