bisphosphoglycerate mutase

bis·phos·pho·glyc·er·ate mu·tase (bis-fos″fo-glisґər-āt muґtās) [EC 5.4.2.4] an enzyme of the isomerase class that catalyzes the interconversion of 1,3-bisphosphoglycerate and 2,3-bisphosphoglycerate; it requires Mg2+ as a cofactor and is more active in the presence of 3-phosphoglycerate. The reaction produces 2,3-bisphosphoglycerate necessary for glucose catabolism and for erythrocytic regulation of hemoglobin oxygen affinity. Deficient enzyme activity, an autosomal recessive trait, results in a form of hemolytic anemia.

Medical dictionary. 2011.

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  • Bisphosphoglycerate mutase — Protbox Name=2,3 bisphosphoglycerate mutase Photo=Phosphoglycerate mutase 3PGM wpmp.png Caption={! align= center border= 0 ! Enzyme! Phosphoglycerate mutase! ! PDB Code! ! Organism! Yeast HGNCid = 1093 Symbol = BPGM AltSymbols = Chromosome = 7… …   Wikipedia

  • Mutase — A mutase is an enzyme that catalyzes the shifting of a functional group from one position to another within the same molecule. Examples of this are bisphosphoglycerate mutase, which appears in red blood cells and phosphoglycerate mutase, which… …   Wikipedia

  • Phosphoglycerate mutase — protein Name=phosphoglycerate mutase 1 (brain) caption= width= HGNCid=8888 Symbol=PGAM1 AltSymbols=PGAMA EntrezGene=5223 OMIM=172250 RefSeq=NM 002629 UniProt=P18669 PDB= ECnumber=5.4.2.1 Chromosome=10 Arm=q Band=25.3… …   Wikipedia

  • 2,3-Bisphosphoglycerate — Chembox new ImageFile = 2,3 Bisphosphoglycerate.svg ImageFile2 = 2,3 Bisphosphoglycerate.gif IUPACName = 2,3 Bisphosphoglycerate OtherNames = 2,3 diphosphoglycerate Section1 = Chembox Identifiers Abbreviations = 2,3 BPG, 2,3 DPG, 23BPG CASNo =… …   Wikipedia

  • Methylmalonyl-CoA mutase — Rendering based on PDB 2XIJ …   Wikipedia

  • Diphosphoglycérate mutase — Diphosphoglycérate mutase. Structure cristalline d un dimère de diphosphoglycérate mutase humaine …   Wikipédia en Français

  • 2,3-bisphosphoglycerate — An intermediate in the Rapoport Luebering shunt, formed between 1,3 bisphosphoglycerate and 3 phosphoglycerate; an important regulator of the affinity of hemoglobin for oxygen; an intermediate of phosphoglycerate mutase. b. mutase an enzyme of… …   Medical dictionary

  • phosphoglycerate mutase — phos·pho·glyc·er·ate mu·tase (fos″fo glisґər āt muґtās) [EC 5.4.2.1] an enzyme of the isomerase class that catalyzes the interconversion of 3 phosphoglycerate and 2 phosphoglycerate, a step in the Embden Meyerhof pathway (see …   Medical dictionary

  • Rapoport-Luebering-Zyklus — Strukturformel von 2,3 Bisphosphoglycerat, dem Intermediat des Rapoport Luebering Zyklus Der Rapoport Luebering Zyklus, auch als Rapoport Luebering Shunt, Rapoport Luebering Shuttle, Phosphoglyceratzyklus oder 2,3 BPG Zyklus bezeichnet, ist in… …   Deutsch Wikipedia

  • 2,3-DPG-Zyklus — Strukturformel von 2,3 DPG, dem Intermediat des Rapoport Luebering Zyklus Der Rapoport Luebering Zyklus, auch als Rapoport Luebering Shunt, Rapoport Luebering Shuttle, Phosphoglyceratzyklus oder 2,3 DPG Zyklus bezeichnet, ist in der Biochemie ein …   Deutsch Wikipedia

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