- ə-meґno asґid de″kahr-bokґsə-lās) [EC 126.96.36.199] an enzyme of the lyase class that catalyzes the decarboxylation of aromatic amino acids, notably converting dopa to dopamine, tryptophan to tryptamine, and hydroxytryptophan to serotonin. The enzyme is bound to a pyridoxal phosphate cofactor and occurs particularly in liver, kidney, brain, and vas deferens; the reaction is important in the biosynthesis of catecholamines and of melanin.
Medical dictionary. 2011.
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